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A number of tools for the alignment of protein-protein interaction (PPI) networks have laid the foundation for PPI network analysis. They typically find conserved interaction patterns by various local or global search algorithms, and then validate the results using genome annotation. The improvement of the speed, scalability and accuracy of network(More)
BACKGROUND The development of a convenient high-throughput gene transduction approach is critical for biological screening. Adeno-associated virus (AAV) vectors are broadly used in gene therapy studies, yet their applications in in vitro high-throughput gene transduction are limited. PRINCIPAL FINDINGS We established an AAV reverse infection (RI)-based(More)
BACKGROUND microRNAs (miRNAs) are small and non-coding RNAs which play critical roles in physiological and pathological processes. A number of methods have been established to detect and quantify miRNA expression. However, method for high-throughput miRNA function detection is still lacking. PRINCIPAL FINDINGS We describe an adeno-associated virus (AAV)(More)
We consider a single circuit-switched communication link, depicted by a Erlang multi-class loss queue, where a customer may vary its required band-width during its service. We obtain approximately the steady-state blocking probability of each class of customer. Comparisons with simulation results show that the approximation solution has a good accuracy. For(More)
—Cloud computing is an emerging computing paradigm that can offer unprecedented scalability and resources on demand, and is getting more and more adoption in the science community, while scientific workflow management systems provide essential support such as management of data and task dependencies, job scheduling and execution, provenance tracking, etc.,(More)