Wendy Munckhof

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The aim of this study was to identify a set of genetic polymorphisms that efficiently divides methicillin-resistant Staphylococcus aureus (MRSA) strains into groups consistent with the population structure. The rationale was that such polymorphisms could underpin rapid real-time PCR or low-density array-based methods for monitoring MRSA dissemination in a(More)
We performed a meta-analysis of randomised clinical studies in which the efficacy and toxicity of the same total daily dose of aminoglycosides administered once-daily was compared with multiple divided daily dosing for treating human infections. Of twenty-eight publications identified from a literature search using Medline 19 publications of 20 study(More)
One approach to microbial genotyping is to make use of sets of single-nucleotide polymorphisms (SNPs) in combination with binary markers. Here we report the modification and automation of a SNP-plus-binary-marker-based approach to the genotyping of Staphylococcus aureus and its application to 391 S. aureus isolates from southeast Queensland, Australia. The(More)
Surgical antibiotic prophylaxis is defined as the use of antibiotics to prevent infections at the surgical site. Prophylaxis has become the standard of care for contaminated and clean-contaminated surgery and for surgery involving insertion of artificial devices. The antibiotic selected should only cover the likely pathogens. It should be given at the(More)
, so the properties associated with STEC in S. sonnei isolates from patients remain undetected. S. sonnei with stx 2a may have potential to cause severe disease, especially in children. This novel and remarkable virulence characteristic in Shigella spp. would affect diagnostics, infection control, and prevention. Acknowledgments We thank the personnel of(More)
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