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OBJECTIVE To characterize those pediatric patients who receive long-term proton pump inhibitors (PPIs) and to determine the safety of long-term use of PPIs in this population. STUDY DESIGN Patient databases were screened for long-term PPI use, defined as more than 9 months of continuous prescription, between 1989 and 2004. RESULTS The median duration of(More)
Nine cases of empyema developing more than three months after pneumonectomy are presented. Diagnosis is difficult; with one exception, all the patients had been ill for at least three weeks and some for several months before the cause was discovered. In four, the radiological demonstration of gas in a previously opaque hemithorax led to the diagnosis. One(More)
Thoracotomy causes severe postoperative pain, which is difficult to manage since the use of systemic analgesics often causes respiratory depression. Cryoanalgesia of the intercostal nerves has been advocated as an effective means of local analgesia without serious side effects. A prospective randomised blind trial to investigate the efficacy of the(More)
BACKGROUND There are longstanding concerns that carcinoid tumours or atrophic gastritis might develop in children receiving proton pump inhibitors (PPIs) long term. In children, this has not been studied using stains sensitive and specific for enterochromaffin-like (ECL) cells. AIM To evaluate gastric biopsies for ECL hyperplasia or gastric atrophy, in(More)
In the treatment of instrumental perforation of the obstructed thoracic oesophagus, relief of obstruction is one of the prerequisites of success. In some cases it is better to resect both the perforation and the original lesion rather than to rely on repair and drainage. The salient features of 19 cases of emergency oesophagectomy collected from the(More)
Intrathoracic fibromas are uncommon but distinctive tumours. They are usually considered to be benign. The origin of these growths, which appear to be primary pleural tumours, has given rise to a diversity of opinion. The literature is confusing, for essentially similar tumours are reported by a variety of names, of which the most common are intrathoracic(More)
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