Wendy A Myers

  • Citations Per Year
Learn More
Psoriasis is a chronic skin disorder affecting approximately 1% to 3% of the world's population. A considerable proportion of patients with psoriasis will develop a form of inflammatory arthritis known as psoriatic arthritis whose prevalence is poorly defined. Significant advances have been made in determining the pathophysiology of both of these diseases,(More)
Alefacept is a dimeric fusion protein that consists of the extracellular CD2-binding portion of human lymphocyte function-associated antigen-3, which is linked to the Fc segment of human IgG1. Alefacept inhibits T-cell activation and proliferation, and induces apoptosis of memory-effector (CD45RO+) T cells in vitro, limiting the inflammatory and(More)
Efalizumab is a humanized anti-CD11a monoclonal IgG(1) antibody approved for the treatment of moderate-to-severe plaque psoriasis. This case report describes two cases of new-onset debilitating psoriatic arthritis in patients with plaque psoriasis on long-standing efalizumab therapy, despite the fact that their skin disease was in remission. Although during(More)
Psoriasis and psoriatic arthritis are chronic inflammatory diseases that significantly affect patients' quality of life. Not only do these diseases impact patients' physical well-being, but also detrimentally affect their life socially and psychologically. There are many different patterns of skin and joint involvement. Understanding the pathogenesis of(More)
A grade of A was given in an introductory statistics course for meeting a set of contingencies that included no work outside of class (except by request), near-perfect performance on exams following each unit of work in a programmed text, correction of all exam errors, self pacing of work, and the chance to finish the course early. A grade of incomplete was(More)
  • 1