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High-resolution diffusion MRI can provide the ability to resolve small brain structures, enabling investigations of detailed white matter architecture. A major challenge for in vivo high-resolution diffusion MRI is the low signal-to-noise ratio. In this work, we combine two highly compatible methods, ultra-high field and three-dimensional multi-slab(More)
PURPOSE Increasing acquisition efficiency is always a challenge in high-resolution diffusion tensor imaging (DTI), which has low signal-to-noise ratio and is sensitive to reconstruction artifacts. In this study, a parallel imaging (PI) and compressed sensing (CS) combined framework is proposed, which features motion error correction, PI calibration, and(More)
Intraductal papillary mucinous neoplasms (IPMNs) have malignant potential and can progress from low- to high-grade dysplasia to invasive adenocarcinoma. The management of patients with IPMNs is dependent on their risk of malignant progression, with surgical resection recommended for patients with branch-duct IPMN (BD-IPMN) who develop high-risk features.(More)
PURPOSE To present a HOmologous Black-Bright-blood and flexible Interleaved imaging (HOBBI) sequence for dynamic contrast-enhanced magnetic resonance imaging (MRI) of the vessel wall. THEORY AND METHODS A HOBBI sequence is proposed to acquire high-spatial-resolution black-blood and high-temporal-resolution bright-blood dynamic contrast-enhanced images in(More)
Total pancreatectomy (TP) may be considered for diffuse disease of the pancreas. However, the quality of life (QOL) implications of TP have not been well studied in the contemporary era. We report the QOL and cause of death after TP. 186 patients underwent TP between 2000 and 2013. The 100 who were still alive at last follow-up were sent a questionnaire(More)
PURPOSE A typical clinical MR examination includes multiple scans to acquire images with different contrasts for complementary diagnostic information. The multicontrast scheme requires long scanning time. The combination of partially parallel imaging and compressed sensing (CS-PPI) has been used to reconstruct accelerated scans. However, there are several(More)
PURPOSE To propose a method to reduce the slab boundary artifacts in three-dimensional multislab diffusion MRI. METHODS Bloch simulation is used to investigate the effects of multiple factors on slab boundary artifacts, including characterization of residual errors on diffusion quantification. A nonlinear inversion method is proposed to simultaneously(More)
Diffusion magnetic resonance imaging (MRI) is a standard imaging tool in clinical neurology, and is becoming increasingly important for neuroscience studies due to its ability to depict complex neuroanatomy (eg, white matter connectivity). Single-shot echo-planar imaging is currently the predominant formation method for diffusion MRI, but suffers from(More)
PURPOSE Nonlinear reconstruction can suppress pseudo-incoherent aliasing artifacts from variable-density spiral (VDS) trajectories when interleaves are undersampled for acquisition acceleration during MR imaging. However, large-scale aliasing artifact suppression often conflicts with fine-scale structure preservation and may cause deterioration of image(More)
OBJECTIVE Our objective was to develop an approach for selecting combinatorial markers of pathology from diverse clinical data types. We demonstrate this approach on the problem of pancreatic cyst classification. MATERIALS AND METHODS We analyzed 1026 patients with surgically resected pancreatic cysts, comprising 584 intraductal papillary mucinous(More)