Wenbo Zhu

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BACKGROUND Astrocytomas are the most common and aggressive brain tumors characterized by their highly invasive growth. Gain of chromosome 7 with a hot spot at 7q32 appears to be the most prominent aberration in astrocytoma. Previously reports have shown that microRNA-335 (miR-335) resided on chromosome 7q32 is deregulated in many cancers; however, the(More)
Most load aware protocols for ad hoc networks use queue size as the main traffic load metric. However, this metric does not reflect the impact of channel contention from neighbor nodes. In this paper, we propose a load-aware routing protocol using two load metrics for route selection, which include MAC layer channel contention information, and the number of(More)
Glioma is the most common malignant cancer affecting the central nerve system, with dismal prognosis. Differentiation-inducing therapy is a novel strategy that has been preliminarily proved effective against malignant glioma. We have reported previously that activation of cAMP/protein kinase A (PKA) pathway is capable of inducing glioma cell(More)
Hosts in mobile ad hoc networks (MANET) are capable of self-configuration and they can migrate at will, which makes the network topology highly dynamic. Thus, routes may break easily since the data session fails when one node moves out of the sensing range of its partner. Besides that, if overused, nodes tend to drain their power completely due to the(More)
—In multihop ad hoc networks over 802.11, the real bandwidth-delay product (BDP) cannot reach a value as large as in wired networks due to contention through wireless shared channels. As a result, conventional congestion-control algorithms cause an overshooting window problem and result in poor throughput in ad hoc networks. In this paper, we split the real(More)
This paper proposes a system model that unifies different optimistic algorithms designed for deploying geographically replicated services in a cloud environment. The proposed model thereby enables a generalized solution (COLOR) by which well-specified safety and timeliness guarantees are achievable in conjunction with tunable performance requirements. The(More)
In the reactive routing algorithms of mobile ad hoc networks (MANET), preemptive routing method tries to warn the source node and to tell it to change route in time before a link is about to break. This method alleviates the problem from packet losses, and shortens the delay of route change after a route failure. However, it also decreases the number of(More)
Transient receptor potential melastatin 7 (TRPM7), a Ca 2+-permeable channel, has been demonstrated to be present in cancer cells and involved in their growth and proliferation. The present study used midazolam, a benzodi-azepine class anesthesic, to pharmacologically intervene in the expression of TRPM7 and to inhibit cancer cell proliferation. Midazolam(More)
Along with the reactive routing algorithms of mobile ad hoc network (MANET), preemptive routing is a patch method which tries to warn the source node and to tell it to change route in time before a link is about to break Preemptive method was proposed to decrease packet losses and improve TCP performance in MANET. However, the precision of warning occasion(More)