Wenbo Wang

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Glycans on the human immunodeficiency virus (HIV) envelope glycoprotein (Env) play an important role in viral infection and evasion of neutralization by antibodies. In this study, all 25 potential N-linked glycosylation sites (PNGS) on the HIV-1 CRF07_BC Env, FE, were mutated individually to study the effect of their removal on viral infectivity, virion(More)
A novel approach of dynamic graphic software watermark is proposed. In this scheme, many fake watermarks created through encoding multi-constant, which's structure is similar to the only true one's, are introduced to enhance the stealth and anti-attack ability of dynamic graph watermark and keep software from sabotage. Meanwhile, a detailed analysis in(More)
BACKGROUND The vaccinia virus Guang9 strain (VG9), derived from the vaccinia virus Tian Tan strain (VTT) has been found to be less virulent than VTT. METHODOLOGY/PRINCIPAL FINDINGS To investigate whether VG9 could be a potential replicating virus vector, the TK genes in VG9 and VTT were replaced with the HIV-1 envelope gene via homologous recombination,(More)
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