Wenbo Wang

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Glycans on the human immunodeficiency virus (HIV) envelope glycoprotein (Env) play an important role in viral infection and evasion of neutralization by antibodies. In this study, all 25 potential N-linked glycosylation sites (PNGS) on the HIV-1 CRF07_BC Env, FE, were mutated individually to study the effect of their removal on viral infectivity, virion(More)
A novel approach of dynamic graphic software watermark is proposed. In this scheme, many fake watermarks created through encoding multi-constant, which's structure is similar to the only true one's, are introduced to enhance the stealth and anti-attack ability of dynamic graph watermark and keep software from sabotage. Meanwhile, a detailed analysis in(More)
BACKGROUND The vaccinia virus Guang9 strain (VG9), derived from the vaccinia virus Tian Tan strain (VTT) has been found to be less virulent than VTT. METHODOLOGY/PRINCIPAL FINDINGS To investigate whether VG9 could be a potential replicating virus vector, the TK genes in VG9 and VTT were replaced with the HIV-1 envelope gene via homologous recombination,(More)
This research proposes that consumers hold " lay theories of medicine " that guide their preferences and behaviors in the health domain. Lay theories of medicine incorporate lay beliefs about illnesses and symptoms (i.e., a form of lay diagnosis that may feature causal [un]certainty) and lay beliefs about health remedies (i.e., a treatment function that(More)
Urothelial carcinoma of the bladder has become a major cause of morbidity, mortality, and health-related costs. There is still no standard instillation therapy against bladder cancer. A meta-analysis was conducted to evaluate the efficacy and toxicity of adding che-motherapy to Bacillus Calmette–Guerin (BCG) in intermediate-and high-risk nonmuscle invasive(More)
Preliminary and incomplete, please do not circulate without the authors' permission. We investigate the causal effect of tweets on product demand using variation in microblogging caused by a partial block of the Chinese microblogging platform Sina Weibo due to political events. We analyze the effect of the activity decrease due to the block on viewership of(More)
We leverage a temporary block of the Chinese microblogging platform Sina Weibo due to political events to estimate the causal e↵ect of user-generated microblogging content on product demand in the context of TV show viewership. Using a set of di↵erence-in-di↵erences regressions, we show viewership decreased more strongly in geographical areas with a higher(More)