Learn More
PLGA nanoparticles simultaneously loaded with vincristine sulfate (VCR) and verapamil hydrochloride (VRP) were prepared via combining O/W emulsion solvent evaporation and salting-out method. Ten independent processing parameters and two materials characteristics were assessed systematically to enhance the incorporation of the two hydrophilic low molecular(More)
This study used time-series of NDVI datasets at a spatial resolution of 8 km and 15-day interval to identify the spatial patterns of cropland phenology in China. To do so, a smoothing algorithm based on an asymmetric Gaussian function was first performed on NDVI dataset to minimize the effects of anomalous values caused by atmospheric haze and cloud(More)
Climate change is now affecting global agriculture and food production worldwide. Nonetheless the direct link between climate change and food security at the national scale is poorly understood. Here we simulated the effect of climate change on food security in China using the CERES crop models and the IPCC SRES A2 and B2 scenarios including CO2(More)
Polymer-based local drug delivery system may be suitable for the treatment of cervix cancer. A pilot study was carried out to examine the efficacy of cisplatin-loaded poly(ethylene oxide)/polylactide composite electrospun nanofibers as a local chemotherapy system against cervical cancer in mice via vaginal implantation. The nanofibers were proven to have(More)
BACKGROUND The Cyclooxygenase-2 (COX-2) rs20417 polymorphism has been implicated in coronary artery disease (CAD) risk, but individually published studies have shown inconsistent results. The aim of this study was to clarify the effects of COX-2 rs20417 polymorphism on CAD risk. METHODS A systematic literature search up to October 27, 2013 was carried out(More)
PURPOSE To evaluate prognostic factors for stent patency and survival in patients with perihilar cholangiocarcinoma (pCCA) who underwent percutaneous biliary stent placement. MATERIALS AND METHODS This prospective study followed 92 consecutive patients with pCCA who underwent metal stent placement between January 2013 and July 2014. Of the total number of(More)
BACKGROUND/AIMS Amelioration of intestinal dysmotility and stasis during the early period of acute necrotizing pancreatitis (ANP) appears to be important to reduce the risks of secondary pancreatic infection. We aimed to characterize the association between the neuropathy of the enteric nervous system and gut dysfunction and to examine the effect of(More)
T ransjugular intrahepatic portosystemic shunt (TIPS) is a well-established treatment for complications arising from portal hypertension. However, hepatic encephalopathy (HE) is a common complication after TIPS insertion. The incidence rate of HE after TIPS insertion is 15%-48%. TIPS implantation with or without gastroesophageal variceal embolization(More)
OBJECTIVES The mechanism of pain in chronic pancreatitis (CP) has yet to be explored. Proteinase-activated receptor 2 (PAR2) plays a pronociceptive role in visceral pain. The study aimed to assess the expression of PAR2 in dorsal root ganglia (DRGs) and validate its role of thermal hyperalgesia in CP. METHODS Chronic pancreatitis model was induced by(More)