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PD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell lymphoma
TLDR
PD-L1 expression positively correlated LMP1 expression in NKTCL, which was probably mediated by the MAPK/NF-κB pathway, and has significant prognostic value for early-stageNKTCL. Expand
Sites of metastasis and overall survival in esophageal cancer: a population-based study
TLDR
Site of metastasis affects survival in metastatic EC; OS was worst for bone metastases and greatest for distant lymph node metastases. Expand
Radiotherapy and PGEMOX/GELOX regimen improved prognosis in elderly patients with early-stage extranodal NK/T-cell lymphoma
TLDR
In conclusion, RT played an important role for elderly patients with early-stage NKTCL, and the PGEMOX/GELOX regimen was superior to other regimens and the combination of them may be a promising treatment option. Expand
The effect of distant metastases sites on survival in de novo stage-IV breast cancer: A SEER database analysis
TLDR
Patients with liver and brain metastases were more likely to experience poor prognosis for breast cancer–specific survival and overall survival by various breast cancer subtypes, and hormone receptor+/human epidermal growth factor receptor 2+ disease was associated with the best prognosis. Expand
The impact of examined lymph node count on survival in squamous cell carcinoma and adenocarcinoma of the uterine cervix
TLDR
The number of ELNs is an independent prognostic factor in patients with stage IA2–IIB cervical cancer and is associated with better survival outcomes, especially in the node-positive SCC subtype. Expand
Multimodal treatment including hysterectomy improves survival in patients with locally advanced cervical cancer: A population-based, propensity score-matched analysis.
TLDR
The results suggest that multimodal treatment including hysterectomy might improve survival outcomes in patients with locally advanced cervical SCC, especially for stage IIB disease. Expand
Downregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3
TLDR
Results indicate that hsa_circ_0011946 and RFC3 comprise a novel pathway involved in the progression of breast cancer. Expand
Di‐(2‐ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPAR&ggr;
TLDR
The results of in vitro experiments could determine that the DEHP‐induced activation of peroxisome proliferator activated receptor (PPAR) played a key role in the production of oxidative stress and down‐regulated expression of insulin receptor and GLUT4 proteins in L02 cells. Expand
Survival in signet ring cell carcinoma varies based on primary tumor location: a Surveillance, Epidemiology, and End Results database analysis
TLDR
Investigation of patients with signet ring cell carcinoma based on primary tumor location suggested a major difference in survival of SRCC based on the primary tumor locations, while breast and colorectal SRCC had better survival than gastric SRCC. Expand
Inflammatory breast cancer outcomes by breast cancer subtype: a population-based study.
TLDR
Breast cancer subtype is clinically useful for predicting survival outcome in IBC, but the HoR+/her2- subtype shows poorer survival outcome than HoR-/HER2+ subtype. Expand
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