Neonatal rat infection with Borna disease virus (BDV), termed neonatal Borna disease, is an established model for investigating the BDV-associated pathogenesis of neurodevelopmental abnormalities. BDV produces a persistent noncytolytic infection in all culture cell systems assayed to date, while persistent infection in neonatal rats results in a progressive… (More)
BACKGROUND Coronary atherosclerotic heart disease (CHD) is one of the major concerns in type 2 diabetes (T2D). The systemic chronic inflammation has been postulated to bridge the increased risk of cardiovascular disease and T2D. We formulated that increased peripheral proinflammatory T helper subsets contributed to the development of cardiovascular… (More)
Ovarian cancer is one of the most common malignancies encountered in the world. In ovarian cancer tissues of patients, NEU1 was expressed in a higher level than that in adjacent normal tissues. In this research, we aimed to elucidate the role of NEU1 siRNA on proliferation, apoptosis, and invasion of OVCAR3 and SKOV3 cells which expressed NEU1 notably. By… (More)
Mounting evidence suggests that endogenous progenitor cells may initiate cerebral WM repair. This study was designed to determine whether endogenous glial progenitor cells derived from either the subventricular zone (SVZ) or the white matter (WM) contribute to WM repair in a neonatal rat model of ischemic periventricular leukomalacia (PVL). Additionally,… (More)
In the title compound, [Fe(C(5)H(5))(2)(C(13)H(11)N(2)O(2))], the dihedral angle between the benzene ring and the cyclo-penta-diene ring bonded to the carbonyl group is 26.1 (2)°. In the crystal, bifurcated O-H⋯(O,N) and N-H⋯O hydrogen bonds link the mol-ecules into a three-dimensional network.
—Scalability and Latency are the two important performance indicators for the distributed file system, and Google and Apache have achieved a great success with GFS and HDFS when operating big files, but the latency is too long when reading and writing small-size files, because the concurrent I/O can't work for small files, besides the master node is… (More)
HIV-1 integrase (HIV-1 IN), a key element of HIV-1-derived lentiviral vectors, is crucial for the stable maintenance of the vector gene by inserting them into host genome. HIV-1 IN has been found to have functions other than integration, such as involving in virion morphology, viral DNA synthesis and viral DNA nuclear import. In our study, the yeast… (More)