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Triiodothyronine modulates cell proliferation of human prostatic carcinoma cells by downregulation of the B‐Cell translocation gene 2
Studies suggest that triiodothyronine (T3) and cognate nuclear receptors (hTR) are involved in regulation of prostatic cell growth and differentiation. To probe mechanisms for T3 effects, we studiedExpand
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Thioredoxin-interacting protein: an oxidative stress-related gene is upregulated by glucose in human prostate carcinoma cells.
Thioredoxin-interacting protein (TXNIP), also known as vitamin-D(3) upregulated protein 1, interacts with reduced thioredoxin. This protein modulates the cellular redox state and plays a role inExpand
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Association between the serotonin transporter and cytokines: Implications for the pathophysiology of bipolar disorder.
BACKGROUND Reduced brain serotonin transporter (SERT) has been demonstrated in bipolar disorder (BD). The aim of this study was to explore the potential role of cytokines on reduced SERT in BD. Expand
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Expression of interleukin-6 is downregulated by 17-(allylamino)-17-demethoxygeldanamycin in human prostatic carcinoma cells
AbstractAim:Interleukin-6 (IL-6) is a pleiotropic cytokine that is associated with tumor metastasis and prostate cancer. We evaluated the mechanism and effect ofExpand
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PS169. Disruption of relationship between serotonin transporter and hippocampal volumes in first-episode drug-naïve major depressive disorder
s | 61 67%±13%). Functional MRI revealed decreased activation in the right inferior frontal (rIFC, pFWE-cluster=0.02) and left middle temporal gyri (lMTG, pFWE-cluster=0.03) to negative facesExpand
PS192. A study of tryptophan, kynurenine and serotonin transporter in first-episode, drug-naïve patients with major depressive disorder
Objective: Early antidepressant response predicts later treatment outcome in patients with major depressive disorder (MDD) [1]. MDD is characterized by changes to the behavioral and neuronalExpand