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Direct phosphorylation of GluA1 by PKC controls α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor (AMPAR) incorporation into active synapses during long-term potentiation (LTP). Numerous signalling molecules that involved in AMPAR incorporation have been identified, but the specific PKC isoform(s) participating in GluA1 phosphorylation(More)
a r t i c l e i n f o a b s t r a c t This paper compares different solution methods for computing the equilibrium of dynamic stochastic general equilibrium (DSGE) models with recursive preferences such as those in Epstein and Zin (1989, 1991) and stochastic volatility. Models with these two features have recently become popular, but we know little about(More)
Radio Frequency Identification (RFID) technology not only offers tracking capability to locate equipment, supplies and people in real time, but also provides efficient and accurate access to medical data for health professionals. However, the reality of RFID adoption in healthcare is far behind earlier expectation. This study reviews literature on the use(More)
Keywords: Complex event processing RFID Smart hospital Healthcare Surgery a b s t r a c t RFID technology has been examined in healthcare to support a variety of applications such as patient identification and monitoring, asset tracking, and patient–drug compliance. However, managing the large volume of RFID data and understanding them in the medical(More)
Glycine in the hippocampus can exert its effect on both synaptic NMDA receptors (NMDARs) and extrasynaptic functional glycine receptors (GlyRs) via distinct binding sites. Previous studies have reported that glycine induces long-term potentiation (LTP) through the activation of synaptic NMDARs. However, little is known about the potential role of the(More)
We propose CONFlexFlow (Clinical cONtext based Flexible workFlow) as a novel approach for integrating clinical pathways into Clinical Decision Support Systems (CDSS). It recognizes that clinical pathways involve frequent deviations and require considerable flexibility. Thus, integration of flexible pathways is critical for the success of CDSS. Further, it(More)
  • Dario Caldaray, Jesús Fernández-Villaverdez, Juan F. Rubio-Ramírezx, Wen Yao, Larry Christiano, Dirk Krueger +1 other
  • 2009
We thank Michel Juillard for his help with computational issues and Larry Christiano, Dirk Krueger, Pawel Zabczyk, and participants at the Penn Macro lunch for comments. Beyond the usual disclaimer, we must note that any views expressed herein are those of the authors and not necessarily those of the Federal Reserve Bank of Atlanta or the Federal Reserve(More)
Regulation of neuronal NMDA receptor (NMDAR) is critical in synaptic transmission and plasticity. Protein kinase C (PKC) promotes NMDAR trafficking to the cell surface via interaction with NMDAR-associated proteins (NAPs). Little is known, however, about the NAPs that are critical to PKC-induced NMDAR trafficking. Here, we showed that(More)
The main idea in this paper is to show how flexible processes can be designed by combining generic process templates and business rules. At run time we first instantiate a process by applying rules to specific case data and using a materialization algorithm. The customized process instance is then executed in an existing workflow engine. We present an(More)