Wen-Yan Tang

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OBJECTIVE To establish an liquid chromatography-mass spectrometry (HPLC-MS/MS)-based method for determining escitalopram in human plasma. METHODS A liquid-liquid ether extraction approach was adopted using dextromethorphan as the internal standard. The Agilent ZORBAX SB-C18 (3.5 microm,2.1 x 150 mm) was used as the analytical column with(More)
This article analyses the characteristic of time frequency distribution of laser detection signals of underwater acoustic signal, we discover the regularity of wavelet ridges distribution of laser interference signal: some wavelet ridges distribute on the scale-time curve which is corresponding with the frequency of underwater acoustic signal, or(More)
A Collaborative Design Frame based on Virtual Prototype and virtual Manufacturing (CDFVPM) is explored. In CDFVPM, the Virtual Product Prototype (VPP) used as a product shared information database, and to view the product during design process before creation of any physical prototype, to detect the product's performance by simulating the product's working(More)
OBJECTIVE To evaluate the bioequivalence of tiopronin enteric capsules (testing preparation, T) versus tablets (reference preparation, R). METHODS A single oral dose of tiopronin enteric capsules or tablets at 200 mg was administered in 2 groups of Chinese healthy volunteers (n=9) in a randomized crossover design at the interval of 2 weeks. The plasma(More)
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