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Prediction of metal bioaccumulation and toxicity in aquatic organisms has been based on the free ion activity (e.g., FIAM) or more recently on the binding with the biological/toxicological sites of action (e.g., biotic ligand model). However, metals are bound to various intracellular ligands that may control metal toxicity. In this study, we examined the(More)
We examined maternal transfer efficiency, retention by subsequent generations, and transgenerational toxicity of methylmercury (CH3Hg or MeHg) in a population of freshwater zooplankton (Daphnia magna). The effect of dietary MeHg residence time in the daphnids on the efflux system also was quantified. After ingesting a relatively high dosage of MeHg, D.(More)
Over the past decades, comparative physiology and biochemistry approaches have played a significant role in understanding the complexity of metal bioaccumulation in aquatic animals. Such a comparative approach is now further aided by the biokinetic modeling approach which can be used to predict the rates and routes of metal bioaccumulation and assist in the(More)
Maximum acceptable concentrations of metals in food - based on total concentrations - have been established in many countries. To improve risk assessment, it would be better to take into account bioaccessible concentrations. A total of seven species of molluscs from France, UK and Hong Kong was examined in this study including clams, mussels, oysters,(More)
We examined the accumulation, subcellular distribution, and toxicity of Hg(II) and MeHg in three marine phytoplankton (the diatom Thalassiosira pseudonana, the green alga Chlorella autotrophica, and the flagellate Isochrysis galbana). For MeHg, the inter-species toxic difference could be best interpreted by the total cellular or intracellular accumulation.(More)
Subcellular metal distribution has received increasing attention in aquatic toxicology studies, but the relationship between metal distribution and metal biokinetics remains largely unexplored. A series of short-term experiments on different concentrations of dissolved and dietary metals and on metal elimination were conducted to investigate the dynamics of(More)
Uptake, absorption efficiency and elimination of DDT were measured in marine phytoplankton, copepods (Acartia erythraea) and fish (mangrove snappers Lutjanus argentimaculatus). The uptake rate constant of DDT from water decreased with increasing trophic level. The dietary absorption efficiency (AE) of DDT was 10-29% in copepods and 72-99% in fish. Food(More)
Harmful algal blooms (HAB) may impose a serious threat to aquatic lives and human health. We determined the effects of a toxic dinoflagellate Alexandrium tamarense (clone ATCIO1, isolated from Hong Kong coastal waters) on the energy budget, quantified as scope for growth (SFG), and the growth rate of the manila clam Ruditapes philippinarum and the(More)