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Ultrasensitive Fluorescent Probes Reveal an Adverse Action of Dipeptide Peptidase IV and Fibroblast Activation Protein during Proliferation of Cancer Cells.
It is found that inhibiting the DPPIV expression with siRNA increases the proliferation rate of MGC803 cells, whereas the FAP inhibition decreases the rate, which provides a new viewpoint for cancer studies. Expand
A tunable ratiometric pH sensor based on carbon nanodots for the quantitative measurement of the intracellular pH of whole cells.
Carbon nanodots labeled with two fluorescent dyes have been developed as a tunable ratiometric pH sensor to measure intracellular pH and shows good biocompatibility and cellular dispersibility. Expand
Rhodamine B thiolactone: a simple chemosensor for Hg2+ in aqueous media.
Rhodamine B thiolactone is developed as a simple chemosensor towards Hg(2+) in neutral aqueous solution with high selectivity.
Near-Infrared Fluorescent Probe with New Recognition Moiety for Specific Detection of Tyrosinase Activity: Design, Synthesis, and Application in Living Cells and Zebrafish.
A new tyrosinase-recognition 3-hydroxybenzyloxy moiety is proposed, which exhibits distinct fluorescence responses for tyosinase and ROS, and effectively eliminates the interference from ROS. Expand
Imaging different interactions of mercury and silver with live cells by a designed fluorescence probe rhodamine B selenolactone.
It is observed that the reaction of Ag(+) with the probe inside the cells occurs much slower than that of Hg(2+), which is ascribed to the high concentration of cellular chloride ions inhibiting the formation of sufficient free Ag(+). Expand
Sensitive fluorescence probe with long analytical wavelengths for γ-glutamyl transpeptidase detection in human serum and living cells.
It is revealed that sodium butyrate can induce the upregulation of GGT in HepG2 cells in a dose- and time-dependent manner and has further been confirmed by lysate assay and inhibitor experiment. Expand
Ultrasensitive Detection of Aminopeptidase N Activity in Urine and Cells with a Ratiometric Fluorescence Probe.
An ultrasensitive ratiometric fluorescent probe (CVN) has been designed and synthesized by incorporating alanine into the cresyl violet fluorophore and reveals significantly higher contents of APN in HepG2 cells than those in LO2 cells, which has been further used to distinguish these two types of cells in mixed cocultures. Expand
Effects of Fluorine Plasma Treatment on Au-Free Ohmic Contacts to Ultrathin-Barrier AlGaN/GaN Heterostructure
Effects of fluorine plasma etching on Au-free ohmic contacts to SiNx-passivated ultrathin-barrier AlGaN/GaN heterostructure were investigated. It is found that overetching of SiNx passivation layer,Expand
In vivo imaging and detection of nitroreductase in zebrafish by a new near-infrared fluorescence off-on probe.
The proposed probe exhibits superior analytical performance such as near-infrared fluorescence emission over 700 nm as well as high selectivity and sensitivity, with a detection limit of 14 ng/mL, and has been successfully applied to visualize the distribution of nit mirroreductase in living zebrafish in vivo, revealing that nitroreductase might mainly exist in zebra fish yolk sac. Expand
Observation of the Generation of ONOO- in Mitochondria under Various Stimuli with a Sensitive Fluorescence Probe.
A mitochondria-targetable fluorescence probe RPTPP is designed and synthesized by using rhodamine as the fluorophore, phenylhydrazine as the recognition moiety, and triphenyl-phosphonium cation as the mitochondrial-targeting moiety to provide a sensitive and selective method for the detection of ONOO-. Expand