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STUDY OBJECTIVES To assess whether changes in psychomotor vigilance during sleep deprivation can be estimated using heart rate variability (HRV). DESIGN HRV, ocular, and electroencephalogram (EEG) measures were compared for their ability to predict lapses on the Psychomotor Vigilance Task (PVT). SETTING Chronobiology and Sleep Laboratory, Duke-NUS(More)
We hypothesized that deterministic tractography is practical and sensitive to changes in the complex nigrostriatal and nigropallidal pathway (NSP) in Parkinson's disease (PD). Using diffusion tensor imaging (DTI) tractography, we investigated the NSP to evaluate differences between PD patients and controls, and examined their clinico-radiologic correlation.(More)
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