Wen-Mei Zhang

Learn More
Platelets are essential for primary hemostasis; however, platelet activation also plays an important proinflammatory role. Inflammation promotes the development of cardiac fibrosis and heart failure induced by hypertension. In this study, we aimed to determine whether inhibiting platelet activation using clopidogrel could inhibit hypertension-induced(More)
Thoracic aortic aneurysm/dissection (TAAD) is characterized by excessive smooth muscle cell (SMC) loss, extracellular matrix (ECM) degradation and inflammation. However, the mechanism whereby signaling leads to SMC loss is unclear. We used senescence-associated (SA)-β-gal staining and analysis of expression of senescence-related proteins (p53, p21, p19) to(More)
Wetland landscape ecological classification, as a basis for the studies of wetland landscape ecology, directly affects the precision and effectiveness of wetland-related research. Based on the history, current status, and latest progress in the studies on the theories, indicators, and methods of wetland landscape classification, some scientific wetland(More)
A simple and accurate method was developed for determining silicon in gasoline using inductively coupled plasma optical emission spectroscopy (ICP-OES). For sample inroduction a Burgener nubulizer and a Cyclonic spray chamber were used. A gasoline sample was diluted with isooctane and then introduced into the cooled spray chamber of the ICP-OES. Good(More)
BACKGROUND/AIMS Hypertension plays a critical role in the cardiac inflammation and injury. However, the mechanism of how hypertension causes the cardiac injury at a molecular level remains to be elucidated. METHODS RNA-Seq has been demonstrated to be an effective approach for transcriptome analysis, which is essential to reveal the molecular constituents(More)
The degeneration of vascular smooth muscle cell(s) (SMC) is one of the key features of thoracic aortic aneurysm and dissection (TAAD). We and others have shown that elevated endoplasmic reticulum (ER) stress causes SMC loss and TAAD formation, however, the mechanism of how SMC dysfunction contributes to intimal damage, leading to TAAD, remains to be(More)
PURPOSE To investigate the effect of premolar extraction on Bolton index overall ratios. METHODS Bolton index overall ratios were measured in 198 randomly chosen dental casts of three types of Angle's malocclusions before and after 4 combinations of hypothetical premolar extractions. The data was processed using SPSS 17.0 software package. RESULTS The(More)
  • 1