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Salinity acclimation enhances salinity tolerance in tadpoles living in brackish water through increased Na⁺ , K⁺ -ATPase expression.
- Chi-Shiun Wu, Wen-Kai Yang, Tsung-Han Lee, I. Gomez‐Mestre, Y. Kam
- Biology, Environmental ScienceJournal of experimental zoology. Part A…
Pre-acclimation to 7 ppt for 48 hr was hence sufficient to activate NKA expression, resulting in increased survivorship and reduced dehydration upon later transfer to 11 ppt, and tadpole osmolality sharply increased and tadpole water content decreased.
Na + /K + -ATPase expression in gills of the euryhaline sailfin molly, Poecilia latipinna, is altered in response to salinity challenge
Involved intrinsic apoptotic pathway in the varicocele and varicose veins.
Expression Profiles of Branchial FXYD Proteins in the Brackish Medaka Oryzias dancena: A Potential Saltwater Fish Model for Studies of Osmoregulation
- Wen-Kai Yang, C. Kang, Chia-Hao Chang, An-Di Hsu, Tsung-Han Lee, P. Hwang
- Environmental Science, BiologyPloS one
- 31 January 2013
The brackish medaka is proposed as a potential saltwater fish model for osmoregulatory studies and the diversity of teleostean FXYD expression profiles is investigated by comparing two closely related euryhaline model teleosts.
Salinity-dependent expression of the branchial Na+/K+/2Cl− cotransporter and Na+/K+-ATPase in the sailfin molly correlates with hypoosmoregulatory endurance
- Wen-Kai Yang, C. Kang, Tzu-Ying Chen, Wen-Been Chang, Tsung-Han Lee
- BiologyJournal of Comparative Physiology B
- 29 March 2011
The correlation between the gradual reductions in expression of branchial NKCC and NKA and decreasing survival rates after hyperosmotic challenge in sailfin molly is illustrated.
Different Modulatory Mechanisms of Renal FXYD12 for Na+-K+-ATPase between Two Closely Related Medakas upon Salinity Challenge
- Wen-Kai Yang, C. Kang, An-Di Hsu, Chia-Hao Lin, Tsung-Han Lee
- BiologyInternational journal of biological sciences
- 28 April 2016
The results of the present study indicated that the kidneys of the examined euryhaline medakas originating from brackish water and fresh water exhibited different modulatory mechanisms through which renal FXYD12 enhanced NKA activity to maintain internal homeostasis.
Increased expression of hypoxia-inducible factor-1alpha and Bcl-2 in varicocele and varicose veins.
A Stenohaline Medaka, Oryzias woworae, Increases Expression of Gill Na+, K+-ATPase and Na+, K+, 2Cl- Cotransporter 1 to Tolerate Osmotic Stress
- Jiun-Jang Juo, C. Kang, Wen-Kai Yang, Shu-Yuan Yang, Tsung-Han Lee
- BiologyZoological Science
- 8 August 2016
The medaka phylogenetic tree indicates that Daisy's medaka belongs to the celebensis species group, and a higher abundance of NKCC1 protein was found in the gill homogenates of the euryhaline medaka, O. woworae, than in that of the stenohaline medaka.
Different expression patterns of renal Na+/K+-ATPase α-isoform-like proteins between tilapia and milkfish following salinity challenges.
Expression and potential roles of sodium-potassium ATPase and E-cadherin in human gastric adenocarcinoma
- Shih‐Ho Wang, Kuan-Lin Wang, Wen-Kai Yang, Tsung-Han Lee, Wan-Yu Lo, Jane-Dar Lee
- Medicine, BiologyPloS one
- 23 August 2017
A significant decrease in NKA function (protein and activity) and E-cadherin in tumor lesions appear promising biomarker for gastric adenocarcinoma, and developing screening methods for detecting NKAfunction may be beneficial for the early diagnosis of gastric cancer.