Wen-Hua Chen

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Kinase insert domain receptor (KDR) inhibitors have been proved to be very effective anticancer agents. Molecular docking, 3D-QSAR methods, CoMFA and CoMSIA were performed on pyrrolo[3,2-d]pyrimidine derivatives as non-ATP competitive KDR inhibitors (type II). The bioactive conformation was explored by docking one potent compound 20 into the active site of(More)
A novel polarized nano-material (PNM) textile is fabricated and characterized at Ka-band (26.5 to 40 GHz) by rectangular waveguide measurements for three different polarization schemes (crossed, horizontal, and vertical polarized samples). Since carbon nanotubes were found to be ultra sensitive to different gases at extremely low concentration, a very(More)
We report the first observation of carbon-induced nanofaceting of a Re single crystal and its application in synthesizing a nanostructured model Pt electrocatalyst investigated using multiple surface science techniques, including low-energy electron diffraction, Auger electron spectroscopy, X-ray photoelectron spectroscopy, low-energy ion scattering, and(More)
Prompt diagnosis and therapy of aneurysms are critical for patients with nontraumatic subarachnoid hemorrhage (SAH). The aim of our study was to assess the clinical usefulness of multislice computed tomography angiography (CTA) in the surgical and endovascular treatment of intracranial aneurysms. A total of 195 cases with 206 intracranial aneurysms(More)
Introduction Since their discovery seventeen years ago, carbon nanotubes (CNTs) have been a subject of intense investigation and have proven useful in a broad range of applications. The prospect of utilizing CNTs covers many interests from gas sensing and shielding to nanotube antennas and other important microwave applications. Different CNT based(More)
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