MicroRNAs (miRNAs) are short, non-coding RNA molecules that play critical roles in human malignancy. However, the regulatory characteristics of miRNAs in triple-negative breast cancer, a phenotype of breast cancer that does not express the genes for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are still poorly… (More)
A 58-year-old woman presented with shuffling gait with small steps for 3 months. Tc-TRODAT-1 dopamine transporter SPECT/CT was prescribed to detect the function of the nigrostriatal system. It disclosed absence of uptake in the left putamen and diffusely decreased uptake in the right striatum. An unexpected mass with uneven uptake over the right frontal… (More)
[This corrects the article DOI: 10.1371/journal.pone.0116610.].
Epidermal growth factor receptor (EGFR) is often constitutively stimulated in many cancers owing to the binding of ligands such as epidermal growth factor (EGF). Therefore, it is necessary to investigate the interaction between EGFR and its targeting biomolecules. The main aim of this study was to estimate the binding affinity and adhesion force of two… (More)
We explore the possibility of implementing real-time fluid simulation on iPhone to create an innovative game experience. Using fluid dynamics and water tri-states as game mechanics, players can manipulate fluid and solve puzzles through the unique input controls of iPhone, such as accelerometer and multi-touch. We implement particle-based fluid simulation… (More)