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BACKGROUND Nowadays, many cytotoxic anticancer drugs exhibit low solubility and poor tumor selectivity, which means that the drug formulation is very important. For example, in the case of paclitaxel (PTX), Cremophor EL(®) (BASF, Ludwigshafen, Germany) needs to be used as a solubilizer in its clinical formulation (Taxol(®), Bristol-Myers Squibb, New York,(More)
A series of novel self-assembled hyaluronic acid derivatives (HA-C(18)) grafted with hydrophobic octadecyl moiety and further dual targeting folic acid-conjugated HA-C(18) (FA-HA-C(18)) were synthesized. With the increase in the degree of substitution of octadecyl group from 12.7% to 19.3%, the critical micellar concentration of HA-C(18) copolymers(More)
PURPOSE To compare the clinical effects of long vs. short intramedullary nails in the treatment of intertrochanteric fractures in old patients more than 65 years old. METHODS A retrospective analysis of 178 cases of intertrochanteric fractures of the femur (AO type A1 and A2) in the elderly was conducted from January 2008 to December 2013. There were 85(More)
Costal cartilage, a type of hyaline cartilage that bridges the bony ribs and sternum, is relatively understudied compared to the load bearing cartilages. Deformities of costal cartilage can result in deformation of the chest wall, where the sternum is largely pushed toward or away from the spine, pectus excavatum and pectus carinatum, respectively, with(More)
Tannase (Tan410) from a soil metagenomic library was immobilized on different supports, including mesoporous silica SBA-15, chitosan, calcium alginate, and amberlite IRC 50. Entrapment in calcium alginate beads was comparatively found to be the best method and was further characterized. The optimum pH of the immobilized Tan410 was shifted toward neutrality(More)
Chinese: there is a significant interaction between toneidentification and tone contexts:(FT1(1,7)=12.37, p<0.05; FT2(1,7)=13.51, p<0.05; FT3(1,7)=48.02, p<0.05; FT4(1,7)=17.34, p<0.05), together with a gradient fromeasy-to-difficult pattern among Chinese:T3+X>X+T3 >T2+X>T1+X>T4+X. They perceive the test contours in these three contexts (+T1, +T2, +T4) as(More)
Multiwavelet transform is a new development to the wavelet theory. It can offer orthogonality, symmetry, and short support simultaneously, and can offer a more precise way for image analysis than wavelet multi-resolution. A new remote-sensing image fusion method based on intensity-hue-saturation transform (IHST) and multiwavelet transform (MWT) is presented(More)
BACKGROUND AND AIMS Deficits in cognitive function are observed during nicotine withdrawal and present a challenge to successful smoking cessation. This clinical trial evaluated a cognitive exercise training (CT) program to improve smoking cessation rates. METHODS Adult treatment-seeking smokers (n=213) were randomized to receive nicotine patch therapy(More)