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The impact of E-cadherin expression on the prognosis of esophageal cancer: a meta-analysis.
TLDR
Reduced E-cadherin expression detected by immunohistochemistry could be a valid prognostic marker in patients with EC, especially in Patients with esophageal squamous cell carcinoma. Expand
High expression of NEDD9 predicts adverse outcomes of colorectal cancer patients.
TLDR
The finding demonstrated the potential value of NEDD9 expression level as a prognostic molecular marker and a target for new therapies for CRC patients. Expand
TNF-α Expression in the UCB-MSCs as Stable Source Inhibits Gastric Cancers Growth in Nude Mice
TLDR
MSC-TNF-α demonstrated a strong suppressive effect on the tumor growth compared with MSC and NaCl, indicating that UCB-MSCs may have the potential to become a prevention approach against gastric cancer. Expand
Gene therapy of gastric cancer using LIGHT-secreting human umbilical cord blood-derived mesenchymal stem cells
TLDR
UCB-MSCs carrying the LIGHT gene have the potential to be used as effective delivery vehicles in the treatment of gastric cancers, and it is found that MSCs with LIGHT were able to significantly induce apoptosis of tumor cells. Expand
Expression of transmembrane protein 41A is associated with metastasis via the modulation of E‑cadherin in radically resected gastric cancer.
TLDR
The expression of TMEM41A was observed to be correlated with lymph node metastasis, distant metastasis and advanced tumor, node and metastasis stages, and may be considered as a novel therapeutic target for the treatment of GC‑associated metastasis. Expand
High expression of NEDD 9 predicts adverse outcomes of colorectal cancer patients
NEDD9, a member of Crk-associated substrate (CAS) family, is highly expressed in multiple cancer types and involved cancer cell adhesion, migration, invasion. The prognostic value of NEDD9 has notExpand
Expression levels of miR-205 and miR-506 in colon cancer tissues and their relationships with clinicopathological features
TLDR
The expression levels of micro ribonucleic acid (miR)-205 and miR-506 are upregulated in the colon cancer patients, both of which may be closely related to the occurrence and development of colon cancer, and may become potential tumor markers as well as relevant therapeutic targets. Expand
circCCDC66 promotes thyroid cancer cell proliferation, migratory and invasive abilities and glycolysis through the miR-211-5p/PDK4 axis
TLDR
It is demonstrated that circCCDC66 could promote TC cell proliferation, migratory and invasive abilities and invasion and glycolysis through the miR-211-5p/PDK4 axis and targeting circCC DC66 may be considered as a promising therapeutic strategy for TC. Expand
Acute appendicitis caused by metastatic gastric adenocarcinoma: a case report and literature review.
It is rare that Acute appendicitis (AA) caused by metastatic gastric adenocarcinoma is seen in the clinic. The underling mechanism is not clear, and the prognoses of these patients have beenExpand
[Effect of synergistic polarization macrophage modulated by N-terminal domain of a2 vacuolar ATPase and macrophage colony stimulating factor on proliferation of gastric cancer cells].
TLDR
A2NTD and M-CSF show a synergistic effect in modulating macrophage phenotype and the secretion of IL-10 and IL-12, which can significantly enhance proliferation of gastric cancer cell strain SGC-7901. Expand
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