Weizhe Liu

Junbing Wu2
Zengqiang Yuan2
2Junbing Wu
2Zengqiang Yuan
Learn More
Oxidative stress influences cell survival and homeostasis, but the mechanisms underlying the biological effects of oxidative stress remain to be elucidated. The protein kinase MST1 (mammalian Ste20-like kinase 1) plays a major role in oxidative stress-induced cell death in primary mammalian neurons. However, the mechanisms that regulate MST1 in oxidative(More)
BACKGROUND Mammalian Ste20-like kinases (MSTs) are the mammalian homologue of Drosophila hippo and play critical roles in regulation of cell death, organ size control, proliferation and tumorigenesis. MSTs exert pro-apoptotic function through cleavage, autophosphorylation and in turn phosphorylation of downstream targets, such as Histone H2B and FOXO(More)
Massive online open courses' (MOOCs') students who use discussion forums have higher chances of finishing the course. However, little research has been conducted for understanding the underlying factors. One of the reasons which hinders the analysis is the amount of manual work required for annotating posts. In this paper we use machine learning techniques(More)
  • 1