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Multicore architectures, especially chip multi-processors, have been widely acknowledged as a successful design paradigm. Existing approaches primarily target application-driven partitioning of the shared cache to alleviate inter-core cache interference so that both performance and energy efficiency are improved. Dynamic cache reconfiguration is a promising(More)
A new method is presented for quantifying proteomic and metabolomic profile data by liquid chromatography-mass spectrometry (LC-MS) with electrospray ionization. This biotechnology provides differential expression measurements and enables the discovery of biological markers (biomarkers). Work presented here uses human serum but is applicable to any fluid or(More)
—System optimization techniques are widely used to improve energy efficiency as well as overall performance. Dynamic voltage scaling (DVS) is acknowledged to be successful in reducing processor energy consumption. Due to the increasing significance of the memory subsystem's energy consumption, dynamic cache reconfiguration (DCR) techniques are recently(More)
—System optimization techniques based on dynamic reconfiguration are widely adopted for energy conservation. While dynamic voltage scaling (DVS) techniques have been extensively studied for processor energy conservation, dynamic cache reconfiguration (DCR) for reducing cache energy consumption in multitasking systems is still in its infancy. In this paper,(More)
—System optimization techniques are widely used to improve energy efficiency as well as overall performance. Dynamic voltage scaling (DVS) is well studied and known to be successful in reducing processor energy consumption. Due to the increasing significance of the memory subsystem's energy consumption, dynamic cache reconfiguration (DCR) techniques are(More)
Cache reconfiguration is a promising optimization technique for reducing memory hierarchy energy consumption with little or no impact on overall system performance. While cache reconfiguration is successful in desktop-based systems, it is not directly applicable in real-time systems due to timing constraints. Existing scheduling-aware cache reconfiguration(More)
Amyloid fibrils are associated with a variety of neurodegenerative maladies including Alzheimer's disease and the prion diseases. The structures of amyloid fibrils are composed of beta-strands oriented orthogonal to the fibril axis ("cross beta" structure). We previously reported the design and characterization of a combinatorial library of de novo(More)
System optimization techniques based on dynamic voltage scaling (DVS) are widely used with the aim of reducing processor energy consumption. Inter-task DVS assigns the same voltage level to all the instances of each task. Its intra-task counterpart exploits more energy savings by assigning multiple voltage levels within each task. In this paper, we propose(More)
Dynamic reconfiguration techniques are widely used for efficient system optimization. Dynamic cache reconfiguration is a promising approach for reducing energy consumption as well as for improving overall system performance. It is a major challenge to introduce cache reconfiguration into real-time embedded systems since dynamic analysis may adversely affect(More)
In recent years, efficient dynamic reconfiguration techniques have been widely employed for system optimization. Dynamic cache reconfiguration is a promising approach for reducing energy consumption as well as for improving overall system performance. It is a major challenge to introduce cache reconfiguration into real-time multitasking systems, since(More)