Weitian Zhong

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Insulin resistance (IR) is a common feature of Type II diabetes, metabolic disorders, hypertension and other vascular diseases. Recent studies showed that obesity-induced inflammation may be critical for IR. To investigate the anti-inflammatory effect of sodium butyrate (NaB) on obesity-induced inflammation, the db/db mice were intraperitoneally injected(More)
Objectives: Altered insulin degrading enzyme function leads to toxic amyloidand insulin aggregates, inflammation, and atherosclerosis. We hypothesized that gene polymorphisms of insulin degrading enzyme (IDE) are associated with the development of coronary heart disease (CHD). Methods: In this case-control study, 231 CHD patients and 200 non-CHD controls(More)
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