Weiqi Chen

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Particle swarm optimization (PSO) is originally developed as an unconstrained optimization technique, therefore lacks an explicit mechanism for handling constraints. When solving constrained optimization problems (COPs) with PSO, the existing research mainly focuses on how to handle constraints, and the impact of constraints on the inherent search mechanism(More)
This paper firstly presents a novel constraint-handling technique , called dynamic-objective method (DOM), based on the search mechanism of the particles of particle swarm optimization (PSO). DOM converts the constrained optimization problem into a bi-objective optimization problem, and then enables each particle to dynamically adjust its objectives(More)
To assess targeting of an epothilone folate conjugate (BMS-753493) to the folate receptor (FR)-overexpressed tumor in mice bearing both FR+ and FR- tumors, a series of experiments were conducted by quantitative whole-body autoradiography (QWBA) and LC-MS/MS following i.v. administration of BMS-753493 or its active moiety, BMS-748285 in mice bearing FR+(More)
The analysis of the passive microwave radiance transfer equation certifies that there is a linear relationship between satellite-generated brightness temperatures (BT) and in situ observation temperature and that land surface temperature (LST) is largely influenced by vegetation cover conditions. Microwave polarization difference index (MPDI) is an(More)