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BACKGROUND The potential of mesenchymal stem cells (MSCs) for immunosuppression has been tested in transplantation, but its mechanisms are not fully understood. This study investigated the role of MSC-expressing B7-H1 in the induction of immune tolerance to cardiac allografts by the combination therapy of MSCs and rapamycin (RAPA). METHODS The(More)
Pancreatic ductal adenocarcinoma (PDAC) is considered to be the most lethal and aggressive malignancy with high mortality and poor prognosis. Their responses to current multimodal therapeutic regimens are limited. It is urgently needed to identify the molecular mechanism underlying pancreatic oncogenesis. Twelve core signaling cascades have been established(More)
Sustainability assessments of coastal beach exploitation are difficult because the identification of appropriate monitoring methodologies and evaluation procedures is still ongoing. In particular, the most suitable procedure for the application of sustainability assessment to coastal beaches remains uncertain. This paper presents a complete sustainability(More)
Cardiac allograft vasculopathy (CAV) is a major complication limiting the long-term survival of cardiac transplants. The role of memory T cells (Tmem) in the pathogenesis of CAV remains elusive. This study investigated the role of Tmem cells in the development of CAV and the therapeutic potential of targeting the OX40/OX40L pathway for heart transplant(More)
Nitrobacteria, nitrification and its impact factors were discussed based on the method of on-site incubation and laboratory simulation in Liaohe estuary wetland sediments in June and August 2009, respectively. The results showed that the number of ammonia-oxidizing bacteria (AOB) ranged from 0.54 x 10(4) to 5.69 x 10(4) cells x g(-1) with an average of(More)
OBJECTIVES Technetium-99m (Tc)-sestamibi is the current radionuclide of choice for parathyroid localization in primary hyperparathyroidism (PH). However, there are only sporadic reports about brown tumor visualization in whole-body Tc-sestamibi scans. This study aimed to systematically evaluate brown tumor uptake in whole-body Tc-sestamibi scans and in(More)
Two cases of brown tumor of the humerus caused by ectopic parathyroid adenomas were presented, which to our knowledge has not been previously documented in the international literature. There are two highlights in these two cases. First, brown tumors of the long bones may commonly involve femur and tibia, rarely involve humerus in association with primary(More)
A brown tumor is a non-neoplasm mainly caused by hyperparathyroidism. It often occurs in the pelvis, ribs, long bone shaft, clavicle, and jaw. We introduce three cases of primary hyperparathyroidism, with the first symptom of brown tumor of the ribs, and discuss the image characteristics within the literature. We then propose the value of ultrasound in the(More)
During recent years, blind image quality assessment (BIQA) has been intensively studied with different machine learning tools. Existing BIQA metrics, however, do not design for stereoscopic images. We believe this problem can be resolved by separating 3D images and capturing the essential attributes of images via deep neural network. In this paper, we(More)
The performance of a sulfidogenic bioreactor and the response of bacterial populations to influent alkalinity changes were investigated. The bioreactor reached 40% of sulfate removal efficiency (SRE) with 0 mg l(-1) of alkalinity, and single-stranded conformation polymorphism profiles showed that some members of Bacteroides, Dysgonomonas, Sporobacter,(More)