Weijun Fang

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The oral administration of amphotericin B (AmB) has a major drawback of poor bioavailability. The aim of this study was to investigate the potential of glyceryl monoolein (GMO) cubosomes as lipid nanocarriers to improve the oral efficacy of AmB. Antifungal efficacy was determined in vivo in rats after oral administration, to investigate its therapeutic use.(More)
OBJECTIVE To observe the method of mechanical ventilation in the chest compressions during cardiopulmonary resuscitation (CPR), and to explore the influence of the flow pattern selection of square-wave and decelerating-wave on airway pressure of patients. METHODS A prospective self-pairing study was conducted. Forty patients undergoing CPR admitted to(More)
Amphotericin B (AmB) is regarded as a life-saving drug in treating severe systemic fungal infections. However, the poor solubility and permeability limits its oral administration. The main purpose of this study is to evaluate AmB nanosuspensions in enhancing its solubility for the oral application. Magnetic stirring method with very low energy input, as a(More)
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