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Agriculture faces great challenges to ensure global food security by increasing yields while reducing environmental costs. Here we address this challenge by conducting a total of 153 site-year field experiments covering the main agro-ecological areas for rice, wheat and maize production in China. A set of integrated soil-crop system management practices(More)
Icaritin (ICT) is a hydrolytic form of icariin isolated from plants of the genus Epimedium. This study was to investigate the radiosensitization effect of icaritin and its possible underlying mechanism using murine 4T1 breast cancer cells. The combination of Icaritin at 3 µM or 6 µM with 6 or 8 Gy of ionizing radiation (IR) in the clonogenic assay yielded(More)
The Fyn related kinase (FRK), a member of intracellular Src-related tyrosine kinases, was recently reported to function as a potent tumor suppressor in several cancer types. However, the expression level and functional significance of FRK in human malignant glioma, which is characterized by high migration and invasion potential, have never been(More)
Dynamic metabolomics studies can provide a systematic view of the metabolic trajectory during disease development and drug treatment and reveal the nature of biological processes at metabolic level. To extract important information in a systematic time dimension rather than at isolated time points, a weighted method based on the means and variations along(More)
Mineral cycling plays a critical role in wetland ecosystem functions and can be affected by environmental changes, such as CO2 enrichment. Learning the responses of mineral bioavailability in wetlands to elevated CO2 under field conditions will provide enormous benefits to the assessment of climate change impacts on wetland ecosystems. A free-air CO2(More)
Temperature and moisture effects on organic carbon (C) decomposition (i.e., CO2 and CH4 emissions) determine the feedback of soil organic carbon (SOC) stocks in rice (Oryza sativa L.) paddies to climate change. In the present study, soils from a long-term (initiated in 1981) fertilization experiment [unfertilized control, combined inorganic nitrogen,(More)
Fyn-related kinase (FRK), a member of Src-related tyrosine kinases, is recently reported to function as a potent tumor suppressor in several cancer types. Our previous study has also shown that FRK over-expression inhibited the migration and invasion of glioma cells. However, the mechanism of FRK effect on glioma cell migration and invasion, a feature of(More)
Developing large rice (Oryza sativa L.) panicles has been widely regarded as an effective approach to increasing rice yield. However, it is unclear whether panicle size affects CH4 emissions from rice fields, especially during the reproductive stage. Here, we conducted two experiments (rice variety and mutant) to examine the effects of rice panicle size on(More)