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In the last decade, inertial microfluidics has attracted significant attention and a wide variety of channel designs that focus, concentrate and separate particles and fluids have been demonstrated. In contrast to conventional microfluidic technologies, where fluid inertia is negligible and flow remains almost within the Stokes flow region with very low(More)
This paper reports on the magnetic propulsion of a spiral-type endoscopic mircorobot in a real small intestine. Magnetic modeling was carried out to design and commission an external electromagnetic system, which wirelessly provides power to the robotic agent. The capsules with different spiral structures were magnetically propelled inside a segment of(More)
The development of a highly controllable drug delivery system (DDS) for capsule endoscopy has become an important field of research due to its promising applications in therapeutic treatment of diseases in the gastrointestinal (GI) tract and drug absorption studies. Several factors need to be considered to establish the minimum requirements for a functional(More)
Separation of cells is a key application area of lab-on-a-chip (LOC) devices. Among the various methods, magnetic separation of cells utilizing microfluidic devices offers the merits of biocompatibility, efficiency, and simplicity. This review discusses the fundamental physics involved in using magnetic force to separate particles, and identifies the(More)
Integrating different steps on a chip for cell manipulations and sample preparation is of foremost importance to fully take advantage of microfluidic possibilities, and therefore make tests faster, cheaper and more accurate. We demonstrated particle manipulation in an integrated microfluidic device by applying hydrodynamic, electroosmotic (EO),(More)
This paper presents an inertial microfluidic device with a simple serpentine micro-channel to continuously separate particles with high performance. Separation of micro/nano-particles has a variety of potential applications in biomedicine and industry. Among the existing separation technologies, a label-free technique without the use of antibody affinity,(More)
This paper presents the development of a new force sensor with MR elastomer as a sensing element. One key element in this study was to find a suitable material with high sensing capabilities which can be used for developing a sensor. Thus different MR elastomers, with ingredients of carbonyl iron particle, graphite, silicone oil and silicone rubber, were(More)
PURPOSE Over the last decade, wireless capsule endoscope has been the tool of choice for noninvasive inspection of the gastrointestinal tract, especially in the small intestine. However, the latest clinical products have not been equipped with a sufficiently accurate localization system which makes it difficult to determine the location of intestinal(More)
Conventional robotic manipulators have been widely studied and proven for their efficiency in macro environment. However, it is unlikely to miniaturize them to mimic a bacterium flagellum type actuator/manipulator. Electroactive polymer (EAP) actuators, also known as artificial muscles, can operate both in wet and dry environments and are very suitable for(More)
This paper reports on the experimental characterization of a robotic drug delivery system based on an endoscopic capsule propelled in water and silicone oil using electromagnetic actuation. Silicon oil is specifically chosen to mimic the viscous environment in the gastrointestinal (GI) tract within the human body. A permanent magnet is embedded inside the(More)