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Previous studies found that cadmium (Cd) could induce apoptosis via interfering with the intracellular calcium (Ca) ions homeostasis. But the detailed mechanisms remain poorly understood. In the present study two cell lines (normal human liver cell HL-7702, and tumor cell Raji cell) were exposed to Cd along or co-incubated with ethylene glycol-bis(More)
The Himalaya region of Nepal provides a habitat for the endangered snow leopard (Panthera uncia) and its principal prey species, the blue sheep (Pseudois nayaur). The aim of this study was to describe the habitat, the distribution and the population structure of blue sheep, and to estimate their contribution to the carrying capacity of snow leopard in the(More)
Cell proliferation plays a critical role in the process of cadmium (Cd) carcinogenesis. Although both induction of reactive oxygen species (ROS) and alteration of DNA methylation are involved in Cd-stimulated cell proliferation, the detailed mechanism of Cd-stimulated cell proliferation remains poorly understood. In this study, K562 cells pre-treated with(More)
Single cell gel electrophoresis or comet assay, micronucleus (MN) test and global DNA methylation detection were used to assess the genotoxicity in toad Bufo raddei exposed to the petrochemical (mainly oil and phenol) polluted area in Lanzhou Region (LZR) comparing with a relatively unpolluted area in Liujiaxia Region (LJXR). The results from the present(More)
In order to assess the condition of heavy metal pollution in the Yellow River, Lanzhou section, China, and to quantify heavy metal (copper, lead, zinc, and cadmium) contents in tissues (liver, kidney, gills, and muscles) of two fish species (Triplophysa pappenheimi and Gobio hwanghensis), levels of these four metals in the water body, sediment, and tissues(More)
This study investigated the soil nematode community structure along the Yellow River in the Lanzhou area of China, and analyzed the impact of heavy metals (Cd, Pb, Cr, Cu, and Zn) and polycyclic aromatic hydrocarbons (PAHs) on the nematode community. Soil samples from five locations (named A-E), which were chosen for soil analysis, showed significant(More)
Data from eight microsatellite loci were used to assess the evolutionary demographic processes of Daurian Partridges from 285 individuals distributed among 23 populations throughout much of the species' distribution range in China. Phylogenetic analysis using microsatellite DNA data indicated that the species were geographically structured and were split(More)
Food resources are often critical regulating factors affecting individual fitness and population densities. In the Himalayan Mountains, Bharal "blue sheep" (Pseudois nayaur) are the main food resource for the endangered snow leopard (Panthera uncia), as well as being preyed upon by other predators. Blue sheep, however, may face a number of challenges(More)
The endangered schizothoracine fish Gymnodiptychus pachycheilus is endemic to the Qinghai-Tibetan Plateau (QTP), but very little genetic information is available for this species. Here, we accessed the current genetic divergence of G. pachycheilus population to evaluate their distributions modulated by contemporary and historical processes. Population(More)
Nepal provides habitat for approximately 100–125 wild Asian elephants (Elephas maximus). Although a small proportion of the world population of this species, this group is important for maintaining the genetic diversity of elephants and conservation of biodiversity in this region. Knowledge of foraging patterns of these animals, which is important for(More)