Weifeng Pi

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AIM To investigate the role of bone morphogenetic protein 2 (BMP-2) in regulation of phosphatase and tensin homologue deleted on chromosome ten (PTEN) and apoptosis of pulmonary artery smooth muscle cells (PASMCs) under hypoxia. METHODS Normal human PASMCs were cultured in growth medium (GM) and treated with BMP-2 from 5-80 ng/ml under hypoxia (5%(More)
The therapeutic effects of acupuncture in treating reproductive disturbances of man and animals have been proven in the past and is used clinically already. However, the mechanism of such therapy is not known yet. In this study, anoestrous sows were used to investigate the mechanism. Anoestrous sows with luteal ovaries were allocated to three groups. Four(More)
Old Long-Evans male rats (24-33 months of age) do show postcastration rise in serum LH but do not have postcastration LH rise in the pituitary both as expressed in content and concentration. The serum LH levels of intact and castrated rats of old age show a tendency of decrease, though not to the level of statistical significance. The pituitary FSH content(More)
Effects of monoamine precursors on food intake in male rats were studied. Rats were subjected to an artificial circadian pattern of eating, i.e., a five-hour feeding program during daytime and food deprived during the rest of day. Feeding responses after treatment of drugs were examined. Intraperitoneal injection of L-beta-3, 4-dihydroxyphenylalanine(More)
A decline in sexual arousal and copulatory activity has been observed in male rats with advancing age. Grafting of fetal hypothalamic tissue into the third ventricle of aged male rats restores sexual behavior. This study investigated the effects of grafting fetal preoptic area (POA) neurons into the POA of aged male rats exhibiting decreased sexual(More)
  • W P Pi
  • 1990
Effects of catecholamines and indoleamine precursors on the luteinizing hormone (LH) release induced by estradiol (E2) and progesterone (P4) in acutely ovariectomized (Ovx) rats were studied. Rats were Ovx on diestrus day 1 (D1) and received a spaced injection of E2 and P4 on D1 and D2, respectively. One of the following substances: L-beta-3,(More)