Weicheng Liu

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beta1,4-galactosyltransferase V (GalT V; EC can effectively galactosylate the GlcNAcbeta1-->6Man arm of the highly branched N-glycans that are characteristic of glioma. Previously, we have reported that the expression of GalT V is increased in the process of glioma. However, currently little is known about the role of GalT V in this process. In(More)
The elevated levels of beta1,4-galactosyltransferase I (GalT I; EC are detected in highly metastatic lung cancer PGBE1 cells compared with its less metastatic partner PGLH7 cells. Decreasing the GalT I surface expression by small interfering RNA or interfering with the surface of GalT I function by mutation inhibited cell adhesion on laminin, the(More)
It has been reported that Salvador (SAV) is a core component of the Salvador-Warts-Hippo (SWH) pathway that restricts cell number, by functioning as a dual regulator of cell proliferation and apoptosis in Drosophila. However, the function of its human ortholog hSav1 (also called hWW45) in mammalian cells is poorly understood. In this study, we identified(More)
A low-voltage/swing clocking methodology is developed through both circuit and algorithmic innovations. The primary objective is to significantly reduce the power consumed by the clock network while maintaining the circuit performance the same. The methodology consists of two primary components: a novel D-flip-flop (DFF) cell that maximizes power savings by(More)
Low swing clocking is a well known technique to reduce dynamic power consumption of a clock network. A novel static D flip-flop topology is proposed that can reliably operate with a low swing clock signal (down to 50% of the V<sub>DD</sub>) despite the full swing data and output signals. The proposed topology enables low swing signals within the entire(More)
A novel level-up shifter with dual supply voltage is proposed. The proposed design significantly reduces the short circuit current in conventional cross-coupled topology, improving the transient power consumption. Compared with the bootstrapping technique, the proposed circuit consumes significantly less area, making it more practical for ICs with a large(More)
This paper approached the feasibility of using the xanthine oxidase (XOD), superoxide dismutase (SOD) and catalase (CAT) activities and malonyldialdehyde (MDA) content in Boleophthalmus pectinirostris liver as the indicators of Cd2+ toxic effects on this marine fish. Three concentrations of cadmium chloride (0.05, 0.5 and 5 mg Cd2+ x L(-1)) were enacted.(More)
Clock skew scheduling is a common and well known technique to improve the performance of sequential circuits by exploiting the mismatches in the data path delays. Existing clock skew scheduling techniques, however, cannot effectively consider heavily gated clock networks where a local clock tree exists between clock gating cells and registers. A methodology(More)
Recent evidence suggests that colonic macrophages and microRNAs play important roles in motor activity in the gastrointestinal tract. However, there are almost no data concerning colonic macrophages and microRNAs in slow transit constipation. The purpose of this study was to investigate colonic macrophages and microRNA-128 expression in the pathogenesis of(More)