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A murine oxidative stress model was established via ozone inhalation, which was identified by detection of the response of antioxidant defense system, levels of oxidative products and effects of natural antioxidants on this model. Male BALB/c mice were exposed to 1.2 mg/m(3) ozone for 10 h per day. The control group was exposed to flowing air. From inhaling(More)
Five new phorbol esters, (four phorbol diesters, 1-4, and one 4-deoxy-4α-phorbol diester, 5), as well as four known phorbol esters analogues (6-9) were isolated and identified from the branches and leaves of Croton tiglium. Their structures were elucidated mainly by extensive NMR spectroscopic, and mass spectrometric analysis. Among them, compound (1) was(More)
A new dimeric sesquiterpene, dicarabrol (1), together with three known sesquiterpenes, carabrol (2), 11(13)-dehydroivaxillin (3), and 2-desoxy-4-epi-pulchellin (4), were isolated from the whole plant of Carpesium abrotanoides L. Their structures were elucidated on the basis of spectroscopic analysis, and single crystal X-ray diffraction analysis. Compound 1(More)
Five new tigliane diterpene esters (1-5), highly oxygenated tetracyclic diterpenoid carbon skeleton, together with three known analogues (6-8) were isolated from the leaves of Croton tiglium. Extensive NMR and mass spectroscopic analysis were used to elucidate their structures. Most of the isolated compounds were tested for their cytotoxic and(More)
OBJECTIVE To study the chemical constituents from ethyl acetate extraction of Sanicula lamelligera. METHODS Compounds were isolated and purified by silica gel and Sephadex LH-20 column chromatographic method, and their structures were identified by using spectroscopic analysis. RESULTS Nine compounds were isolated and identified as angelicin (I),(More)
OBJECTIVE To study the chemical constituents from Carpesium abrotanoides. METHODS Compounds were isolated and pu- rified by silica gel and Sephadex LH-20 column chromatography, their structures were determined by using spectroscopic analysis. RESULTS Ten compounds were isolated and identified as Vomifoliol (I), 2-Desoxy-4-epi-pulchellin (II),(More)
OBJECTIVE The scavenging effects of 8 extracts from several plants used as both medicines and foods on oxygen free radicals were studied in vitro. METHODS Chemiluminescence (CL) method and ultra-weak luminescence technique were used, meanwhile, macrophage respiratiory burst was also carried out to evaluate the antioxidation reaction. RESULTS The(More)
Fifteen compounds, including six quinone/hydroquinone meroterpenoids, purpurogemutantin (1), macrophorin A (2), 4'-oxomacrophorin (3), 7-deacetoxyyanuthone A (4), 2,3-hydro-deacetoxyyanuthone A (5), 22-deacetylyanuthone A (6), anicequol (7), three roquefortine derivatives, roquefortine C (8), (16S)-hydroxyroquefortine C (9), (16R)-hydroxyroquefortine C(More)
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