Wei-hui Zeng

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Survival in host phagocytes is an effective strategy for pathogenic microbes to spread. To understand the mechanisms of Aeromonas hydrophila survival within host macrophages, a library of mini-Tn10 transposon insertion mutants was constructed. The M85 mutant, whose survival in host macrophages was only 23.1% of that of the wild-type (WT) strain, was(More)
OBJECTIVE To study the expression of integrin beta1 in squamous cell carcinoma (SCC) and explore the relationship between stem cell marker and SCC. METHODS The expressions of integrin beta1 in SCC tissues and SCC cell strain A431 were detected with immunohistochemical methods and cell staining method. The differentiation of SCC cells were induced with(More)
OBJECTIVE To investigate the role of psoriasin in mycosis fungoides. METHODS Psoriasin protein expressions in normal skin tissues and mycosis fungoides tissues were detected by immunohistochemistry. RESULTS Psoriasin protein was not expressed in normal skin tissues. In 21 mycosis fungoides tissue specimens, psoriasin was expressed in the stratum corneum(More)
Chinese native buffaloes have faced the threat of extinction, along with an increase in crossbreeding with domesticated river buffaloes; consequently, conservation of local buffalo genetic resources has become a priority. A Chinese native breed, Jianghan, is often crossed intentionally and unintentionally with imported breeds from India and Pakistan,(More)
A novel strategy by means of poly diallyl dimethylammonium chloride (PDDA) was used to make highly mono-dispersed positively charged gold nanoparticles, and 5-ALA was immobilized onto the gold nanoparticles through electrostatic interaction. The conjugation of 5-aminolevulinic acid (5-ALA) and gold nanopartilces were characterized by the integrated tools of(More)
Folate receptor (FR) is particularly upregulated in many epithelial cancer cells membrane and limited distribution is found in normal tissues. In the present work, the folic acid protected gold nanoparticles (FA-GNPs) were synthesized by a simple and quick method, in which chloroauric acid (HAuCl4) was reduced by sodium borohydride (NaBH4) in the presence(More)
OBJECTIVE To investigate the effects of all-trans retinoic acid (ATRA), acitretin and tazarotene on apoptosis and Bax/Bcl-2 protein expressions of human melanoma A375 cells. METHODS The effects of retinoids on apoptosis and Bax/Bcl-2 protein expressions of A375 cells in vitro were examined. Apoptosis analysis with double staining with annexin V-FITC and(More)
OBJECTIVE To investigate the role of tazarotene induced gene-2 (TIG2) in psoriasis vulgaris. METHODS TIG2 protein and mRNA expressions in normal tissues, psoriatic lesions and uninvolved skin tissues were detected by immunohistochemistry and in situ hybridization, respectively. RESULTS TIG2 protein and mRNA were expressed in all the layers of normal and(More)
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