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OBJECTIVE To investigate lyophilization of SM-SLN. METHOD The parameters of lyophilization process was optimized. In addition, the protective effect of various types and concentrations of cryoprotectants were tested by shape, colour and disparity. RESULT The mixture of 2% lactose and 2% glucose could better prevent nanoparticles from aggregating, the(More)
BACKGROUND To comparatively evaluate the cardioprotective activity of placental growth factor (PGF) delivered through direct injection and a nanoparticle-based system respectively and to study the underlying mechanisms in a rat model of acute myocardial infarction (AMI). METHODS Poly lactic-co-glycolic acid (PLGA)-based PGF-carrying nanoparticles(More)
Retraction The Publisher and Editor regretfully retract this article [1] because the peer-review process was inappropriately influenced and compromised. As a result, the scientific integrity of the article cannot be guaranteed. A systematic and detailed investigation suggests that a third party was involved in supplying fabricated details of potential peer(More)
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