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  • Ping-Ping He, Xin-ping Ouyang, +18 authors Chao-ke Tang
  • Biology, Medicine
  • Biochimie
  • 2014 (First Publication: 1 November 2014)
  • BACKGROUND Accumulating evidence suggests that microRNA-590 (miR-590) has protective effects on cardiovascular diseases, but the mechanism is unknown. Interestingly, previous studies from ourContinue Reading
  • Gang Lan, Wei Xie, +9 authors Chao-ke Tang
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2016 (First Publication: 1 April 2016)
  • Angiopoietin-like 4 (Angptl4), a secreted protein, is an important regulator to irreversibly inhibit lipoprotein lipase (LPL) activity. Macrophage LPL contributes to foam cell formation via aContinue Reading
  • Xin Ma, Yan-wei Hu, +6 authors Chao-ke Tang
  • Biology, Medicine
  • Cardiovascular Drugs and Therapy
  • 2009 (First Publication: 1 June 2009)
  • BackgroundThe Niemann–Pick C1 (NPC1) protein regulates the transport of cholesterol from late endosomes/lysosomes to other compartments responsible for maintaining intracellular cholesterolContinue Reading
  • Mei-Hua She, Hongjie Hou, Zong-bao Wang, Chi Zhang, Moshe Laudon, Wei-dong Yin
  • Biology, Medicine
  • Biochimie
  • 2014 (First Publication: 1 August 2014)
  • Melatonin is biosynthesized in the pineal gland and secreted into the bloodstream. Evidences indicate a role of melatonin in the regulation of glucose metabolism. The objective of this study was toContinue Reading