Wei-chang Yu

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OBJECTIVE To investigate the possible relationship between the analgesic effect of acupuncture and connexin 43. METHODS Connexin 43 gene knock-out mice were divided into 4 groups: a wide type (WT) control group, a WT acupuncture group, a heterozygous (HT) control group and HT acupuncture group. Hot-plate test and writhing response induced by acetic acid(More)
BACKGROUND Connexin 43 (Cx43) is one of the major components of human keratinocyte gap junctions. To study whether gap junctional intercellular communication participates in the transfer of acupoint signals and acupuncture analgesia, the expression of Cx43 was studied in Zusanli (ST36) acupoints compared with control non-acupoint regions in rats after(More)
OBJECTIVE To explore the effect of connexin 43 gene knockout on acupuncture analgesia. METHODS Seventy-two wide type (WT) and connexin 43 gene knockout mice were separately and randomly divided into: WT control group, WT model group, WT acupuncture group, heterozygous (HT) control group, HT model group and HT acupuncture group, with 12 cases in each.(More)
OBJECTIVE To explore the relation between gap junction and meridian phenomenon. METHODS The oxygen partial pressure in acupoints [see text for formula] and in their corresponding non-acupoints of the Bladder Meridian was observed with the needle-type tissue oxygen tension sensor in the gap junction blocking goats by 1-Heptanol injection and the Connexin(More)
OBJECTIVE To explore the possible central and peripheral mechanisms of connexin 43 gene knockout in acupuncture analgesia. METHODS Fifty-four wide type (WT) mice and 54 connexin 43 gene knockout (heterozygote, HT) mice were randomly divided into WT control group, WT model group, WT acupuncture group, HT control group, HT model group and HT acupuncture(More)
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