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Overexpression of Shc adaptor proteins is associated with mitogenesis, carcinogenesis and metastasis. Multiple copies in T-cell malignancy 1 (MCT-1) oncoprotein promotes cell proliferation, survival and tumorigenic effects. Our current data show that MCT-1 is a novel regulator of Shc-Ras-MEK-ERK signaling and MCT-1 is significantly co-activated with Shc(More)
AIMS Mitochondrial succinate dehydrogenase (SDH) is an essential complex of the electron transport chain and tricarboxylic acid cycle. Mutations in the human SDH subunit D frequently lead to paraganglioma (PGL), but the mechanistic consequences of the majority of SDHD polymorphisms have yet to be unraveled. In addition to the originally discovered yeast(More)
Background construction is the base of object detection and tracking for the machine vision system. Traditional background modeling methods often require complicated computations and are sensitive to illumination changes and shadow interference. In this paper, we propose a block-based background modeling method, which fully utilizes the color and texture(More)
—In order to conform to the real world systems such as distribution systems and supply chain management system, we assume the capacity of each arc in the quickest path problem is stochastic (multi-state). In this study, we propose a simple algorithm to evaluate the probability that d units of data can be sent from the source node to the sink node through(More)
Centrosome amplification and chromosome abnormality are frequently identified in neoplasia and tumorigenesis. However, the mechanisms underlying these defects remain unclear. We here identify that MCT-1 is a centrosomal oncoprotein involved in mitosis. Knockdown of MCT-1 protein results in intercellular bridging, chromosome mis-congregation, cytokinesis(More)
Microarray data analysis is a major line of research in bioinformatics. A significant trend in bioinformatics is identifying genes or gene groups that differentiate diseased tissues. Classification is necessary to make microarray data useful for application in medicine, and in related research such as disease diagnosis. Classification models have been(More)
Due to the development of technology, electronics have become intertwined with our daily lives. Because of our reliance on such products, they need to be user-friendly, thus, improving current technology products is critical. One example of an electronic product with an opportunity for improvement is the projector. In many places, projectors have become an(More)
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