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BACKGROUND Glandular trichomes produce a wide variety of commercially important secondary metabolites in many plant species. The most prominent anti-malarial drug artemisinin, a sesquiterpene lactone, is produced in glandular trichomes of Artemisia annua. However, only limited genomic information is currently available in this non-model plant species. (More)
A new high order finite-difference method utilizing the idea of Harten ENO subcell resolution method is proposed for chemical reactive flows and combustion. In reaction problems, when the reaction time scale is very small, e.g., orders of magnitude smaller than the fluid dynamics time scales, the governing equations will become very stiff. Wrong propagation(More)
where U , F (U), G(U), H(U) and S(U) are vectors. Here the source term S(U) is restricted to be homogeneous in U ; that is, (x, y, z) and t do not appear explicitly in S(U). If physical viscosities are present, viscous flux derivatives should be added. If the time scale of the ordinary differential equation (ODE) U t = S(U) for the source term is orders of(More)
BACKGROUND Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme for folate metabolism in humans; it is encoded by the MTHFR gene. Several studies have assessed the association between MTHFR C677T polymorphism and the risk of congenital heart defects (CHDs), while the results were inconsistent. METHODS AND FINDINGS Multiple electronic(More)
We develop a multiscale discontinuous Galerkin (DG) method for solving a class of second order elliptic problems with rough coefficients. The main ingredient of this method is to use a non-polynomial multiscale approximation space in the DG method to capture the multiscale solutions using coarse meshes without resolving the fine scale structure of the(More)
INTRODUCTION Glycyrrhizin (GL) was recently found to suppress high-mobility group box 1 (HMGB1)-induced injury by binding directly to it. However, the effect of GL on HMGB1 expression in endotoxemia as well as its underlying molecular mechanism remained unclear. METHODS Twenty-one pigs were divided into four groups: sham group (n=3), control group (n=6),(More)
In this paper, we develop a multiscale local discontinuous Galerkin (LDG) method to simulate the one-dimensional stationary Schrödinger-Poisson problem. The stationary Schrödinger equation is discretized by the WKB local discontinuous Galerkin (WKB-LDG) method, and the Poisson potential equation is discretized by the minimal dissi-pation LDG (MD-LDG)(More)
The goal of this paper is to generalize the well-balanced approach for non-equilibrium flow studied by Wang et al. [29] to a class of low dissipative high-order shock-capturing filter schemes and to explore more advantages of well-balanced schemes in reacting flows. More general 1D and 2D reacting flow models and new examples of shock turbulence(More)
The stiffness of the source terms in modeling non-equilibrium flow problems containing finite-rate chemistry or combustion poses additional numerical difficulties beyond that for solving non-reacting flows. A well-balanced scheme, which can preserve certain non-trivial steady state solutions exactly, may help minimize some of these difficulties. In this(More)
Many studies have reported the association of X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln, Arg194Trp, Arg280His, -77T>C, and X-ray repair cross-complementing group 3 (XRCC3) T241M polymorphisms with lung cancer risk, but the results remained controversial. Hence, we performed a meta-analysis to investigate the association between lung cancer(More)