Wei Tao Huang

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G-quadruplex structure aptamer (PS2.M) can capture acridine orange (AO) from reduced graphene oxide (rGO). When the AO-PS2.M/rGO mixture is incubated with hemin, the specific binding of hemin with PS2.M results in a release of AO from PS2.M and return of AO back to rGO. Based on the quenching of fluorescence, the target hemin was detected sensitively and(More)
Herein, we demonstrate the first use of a reduced graphene oxide (rGO)-organic dye nanoswitch for the label-free, sensitive and selective detection of Hg(2+) using bifunctional rGO as an effective nanoquencher and highly selective nanosorbent. Moreover, a reversible on-off INHIBIT rGO logic gate based on a cysteine-Hg(2+) system has also been designed.
In the present study we develop a relatively novel and effective chaos control approach with a multimode periodic disturbance applied as a control signal and perform an in-depth analysis on this nonfeedback chaos control strategy. Different from previous chaos control schemes, the present method is of two characteristic features: (1) the parameters of the(More)
This work reported a label-free colorimetric assay for sensitive detection of Hg(2+) based on Hg(2+)-triggered hairpin DNA probe (H-DNA) termini-binding and exonuclease Ш (Exo Ш)-assisted target recycling, as well as hemin/G-quadruplex (DNAzyme) signal amplification. The specific binding of free Hg(2+) with the thymine-thymine (T-T) mismatches termini of(More)
Ethynyl triggered enhanced fluorescence quenching effect was first reported based on photoinduced electron transfer (PET) between fluorophore and ethynyl. Ethynyl and 6-carboxyl-fluorescein (FAM) were labeled at the 5'- and 3'-termini of a poly d(T) sequence containing three thymine units, respectively. In the presence of Hg(2+), Hg(2+) binds to two thymine(More)
A new room-temperature phosphorescence (RTP) mercury ions sensor has been developed based on cetyltrimethylammonium bromide-capped Mn-doped ZnS quantum dots (CTAB/Mn-ZnS QDs) and label-free thymine (T)-rich aptamer. The formed T-Hg(2+)-T dsDNA can linearly quench the RTP of Mn-ZnS QDs through electron transfer and aggregation effect, and give a detection(More)
The most serious, and yet unsolved, problem of constructing molecular computing devices consists in connecting all of these molecular events into a usable device. This report demonstrates the use of Boolean logic tree for analyzing the chemical event network based on graphene, organic dye, thrombin aptamer, and Fenton reaction, organizing and connecting(More)
Coupling T base with Hg(2+) to form stable T-Hg(2+)-T complexes represents a new direction in detection of Hg(2+). Here a graphene oxide (GO)-based fluorescence Hg(2+) analysis using DNA duplexes of poly(dT) that allows rapid, sensitive, and selective detection is first reported. The Hg(2+)-induced T(15)-(Hg(2+))(n)-T(15) duplexes make T(15) unable to(More)