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Isolation and characterization of human spermatogonial stem cells
TLDR
The two-step enzyme digestion (by type I collagenase and trypsin) process is an economical, simple and reproducible technique for isolating human spermatogonial stem cells to form a stable cell colony on the supporting cell layer. Expand
Diabetic cystopathy: A review 综述:糖尿病性膀胱病
TLDR
The exact prevalence and pathogenesis of diabetic cystopathy remains to be further investigated and studied in multicenter, large‐scaled, or randomized basic and clinical trials, and a validated and standardized workup needs to be made, improving diabetic cy stopathy management in clinical practice. Expand
Prognostic value of miR-106b expression in breast cancer patients.
TLDR
MiR- 106b was found to be associated with a high risk of recurrence of breast cancer, and miR-106b is a putative plasma marker for risk assessment in patients with breast cancer. Expand
High expression of long non-coding RNA lncRNA-ATB is correlated with metastases and promotes cell migration and invasion in renal cell carcinoma.
TLDR
It is found that long non-coding ribonucleic acid activated by transforming growth factor β knockdown could inhibit cell proliferation, trigger apoptosis, reduce epithelial-to-mesenchymal transition program, and suppress cell migration and invasion during renal cell carcinoma metastasis. Expand
A novel Bifidobacterium infantis-mediated TK/GCV suicide gene therapy system exhibits antitumor activity in a rat model of bladder cancer
TLDR
The results demonstrate that the Bifidobacterium infantis-mediated TK/GCV suicide gene therapy system can effectively inhibit rat bladder tumor growth, possibly through increasing caspase 3 expression and inducing apoptosis. Expand
Histone deacetylase inhibitor valproic acid (VPA) promotes the epithelial mesenchymal transition of colorectal cancer cells via up regulation of Snail
TLDR
Data reveal that VPA can trigger the EMT of CRC cells via up regulation of Snail through AKT/GSK-3β signals and post-transcriptional modification, suggesting that more attention should be paid when VPA is used as a new anticancer drug for CRC patients. Expand
Downregulation of microRNA-132 indicates progression in hepatocellular carcinoma
TLDR
The findings of the present study indicated that miR-132 is downregulated in HCC and may serve as a tumor suppressor in its progression. Expand
Diagnostic and prognostic value of serum MACC1 in breast cancer patients
TLDR
It is demonstrated that circulating MACC1 could serve as a reliable diagnostic and prognostic biomarker for breast cancer and exhibited significant prognostic value in breast cancer. Expand
Promising significance of the association of miR-204-5p expression with clinicopathological features of hepatocellular carcinoma
TLDR
It is suggested that miR-204-5p might act as a tumor-suppressive gene in the tumorigenesis and progression of HCC via vital signaling pathways and thatmiR- 204- 5p could be regarded as a protective factor in HCC. Expand
Targeting c-Met as a promising strategy for the treatment of hepatocellular carcinoma.
TLDR
A second look is taken at the c-Met signal transduction pathway and the possibility of targeting c- met as a therapeutic strategy for HCC treatment is discussed. Expand
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