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The leader-following consensus problem of higher order multi-agent systems is considered. In the system, the dynamics of each agent and the leader is a linear system. The control of each agent using local information is designed and detailed analysis of the leader-following consensus is presented for both fixed and switching interaction topologies, which(More)
In this work, the authors consider the fourth order nonlinear ordinary differential equation u (4) (t) = f (t, u(t)), 0 < t < 1, with the four-point boundary conditions u(0) = u(1) = 0, au (ξ 1) − bu (ξ 1) = 0, cu (ξ 2) + du (ξ 2) = 0, where 0 ≤ ξ 1 < ξ 2 ≤ 1. By means of the upper and lower solution method and fixed point theorems, some results on the(More)
Previous studies have demonstrated the tremendous tropism of mesenchymal stem cells (MSCs) for malignant gliomas, making these cells a potential vehicle for delivery of therapeutic genes to disseminated glioma cells. However, the mechanisms underlying the tropism of MSCs for gliomas remain poorly defined. It has been suggested that malignant gliomas secrete(More)
Avian leukosis virus subgroup J (ALV-J), first isolated in 1989, preferentially infects meat-type birds. However, layer flocks in China have experienced outbreaks of this virus since 2008. To understand the genetic diversity of ALV-J in Chinese layers, we compared and analyzed the GP85 gene sequences of 106 ALV-J isolates that were isolated between 1999 and(More)
The CRISPR/Cas9 system has been adapted as an efficient genome editing tool in laboratory animals such as mice, rats, zebrafish and pigs. Here, we report that CRISPR/Cas9 mediated approach can efficiently induce monoallelic and biallelic gene knockout in goat primary fibroblasts. Four genes were disrupted simultaneously in goat fibroblasts by(More)
We hypothesized that the 5-hydroxytryptamine (5-HT; serotonin) system is present and functional in veins. In vena cava (VC), the presence of the 5-HT synthesis rate-limiting enzyme tryptophan hydroxylase-1 mRNA and accumulation of the 5-HT synthesis intermediate 5-hydroxytryptophan after incubation with tryptophan supported the ability of veins to(More)
OBJECTIVES The thalamus and cerebral cortex are connected via topographically organized, reciprocal connections, which hold a key function in segregating internally and externally directed awareness information. Previous task-related studies have revealed altered activities of the thalamus after total sleep deprivation (TSD). However, it is still unclear(More)
The handling of serotonin [5-hydroxytryptamine (5-HT)] depends on the serotonin transporter (SERT). A SERT knockout (KO) rat is a useful model to test the hypothesis that SERT is the primary mechanism for arterial 5-HT uptake and to investigate the impact of SERT removal on blood pressure. Wild-type (WT) and KO rats were used to measure 5-HT content(More)
Keywords: Multivariable processes Decentralized control Interaction measurement Loop pairing Relative gain array Niederlinski index Relative normalized gain array Controller independent Simulation a b s t r a c t This paper presents a new control-loop configuration criterion for multivariable processes. Both the steady-state and transient information of the(More)