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PURPOSE This study was designed to evaluate the therapeutic effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) on patients with refractory partial epilepsy. METHODS Sixty-four patients with refractory focal epilepsy were screened and 60 patients were randomly divided into two groups by stimulation intensity: 90% (group 1) or 20%(More)
Event-related potentials (ERPs) were recorded in subjects while they were matching two sequentially presented color spots. The two spots might be presented in the same position of the same color, or different colors (color conflict). They might be in different positions of the same color (position conflict), or different colors (color and position(More)
BACKGROUND Abberant aryl hydrocarbon receptor (AhR) expression and AhR pathway activation are involved in gastric carcinogenesis. However, the relationship between AhR pathway activation and gastric cancer progression is still unclear. In present study, we used 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD), a classic and most potent ligand of AhR, to(More)
Seventeen refractory partial epilepsy patients were enrolled in an open-label study to evaluate the antiepileptic effect of low-frequency repetitive transcranial magnetic stimulation (rTMS). Seven of the patients had not obtained seizure-free status after epileptogenic focus resection surgery before they were enrolled in the study. All patients were treated(More)
Mesial temporal lobe epilepsy (MTLE) is a common type of intractable epilepsy characterized by astroglial gliosis. The S100B was viewed as an astrocyte marker and experimental studies indicated that S100B might be involved in the pathophysiology of temporal lobe epilepsy. In this study, we measured plasma S100B levels by ELISA in 28 patients with MTLE and(More)
Hypoxia-induced retinal ganglion cell (RGC) death has been implicated in glaucomatous optic neuropathy. However, the precise mechanism of death signaling and how neuroprotective agents affect it are still unclear. The aim of this study is to characterize the mechanisms of hypoxia-induced apoptosis of cultured purified RGCs and to study the neuroprotective(More)
BACKGROUND Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor associated with gastric carcinogenesis. 3,3'-Diindolylmethane (DIM) is a relatively non-toxic selective AhR modulator. This study was to detect the effects of DIM on gastric cancer cell growth. METHODS Gastric cancer cell SGC7901 was treated with DIM at different(More)
Major depressive disorder (MDD) is a mood disorder that is often accompanied by the impairment of cognitive functions. The aim of this study was to investigate the feasibility of N270 as an index for evaluating the cognitive impairment in MDD patients. Twenty-five patients with MDD diagnosed according to DSM-IV and 25 age matched normal controls performed a(More)
We applied event-related potentials (ERPs) to assess brain activities with inhibition of irrelevant conflict information processing during visual selective attention. Fifteen healthy subjects matched two sequentially presented color spots (S1 and S2) in a visual selective attention task. The two spots might be presented in a fixed position of either the(More)
BACKGROUND Gastrokine-1 (GKN1), a secreted protein, is specifically expressed in gastric mucosa to protect and maintain the integrity of gastric epithelium. The present study investigated differential expression of GKN1 in normal, precancerous, and cancerous gastric tissues, and explored the biological functions of GKN1 protein in gastric cancer cells. (More)