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—Power-coupling models are inherently unable to describe certain mode coupling effects in multimode fiber (MMF) when using coherent sources at high bit rates, such as polarization dependence of the impulse response. We develop a field-coupling model for propagation in graded-index MMF, analogous to the principal-states model for polarization-mode dispersion(More)
AIM To investigate the expression profile of microRNAs in inoperable advanced non-small cell lung cancer (NSCLC) patients receiving chemotherapy and the potential relevance of microRNAs to clinicopathological characteristics and prognosis. METHODS Serum samples were taken from 260 inoperable advanced NSCLC patients and 260 healthy individuals. All the(More)
Hypoxia-induced retinal ganglion cell (RGC) death has been implicated in glaucomatous optic neuropathy. However, the precise mechanism of death signaling and how neuroprotective agents affect it are still unclear. The aim of this study is to characterize the mechanisms of hypoxia-induced apoptosis of cultured purified RGCs and to study the neuroprotective(More)
AIM To explore the association between genetic polymorphisms of the receptor for advanced glycation end-products (RAGE) and susceptibility, chemotherapy response rate and prognosis of non-small cell lung cancer (NSCLC). METHOD This is a prospective study in which 562 patients with NSCLC and 764 healthy controls were enrolled. Three RAGE genetic(More)
BACKGROUND Abberant aryl hydrocarbon receptor (AhR) expression and AhR pathway activation are involved in gastric carcinogenesis. However, the relationship between AhR pathway activation and gastric cancer progression is still unclear. In present study, we used 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD), a classic and most potent ligand of AhR, to(More)