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Person re-identification is to match pedestrian images from disjoint camera views detected by pedestrian detectors. Challenges are presented in the form of complex variations of lightings, poses, viewpoints, blurring effects, image resolutions, camera settings, occlusions and background clutter across camera views. In addition, misalignment introduced by(More)
Human reidentification is to match persons observed in non-overlapping camera views with visual features for inter-camera tracking. The ambiguity increases with the number of candidates to be distinguished. Simple temporal reasoning can simplify the problem by pruning the candidate set to be matched. Existing approaches adopt a fixed metric for matching all(More)
During the priming step that leaves synaptic vesicles ready for neurotransmitter release, the SNARE syntaxin-1 transitions from a closed conformation that binds Munc18-1 tightly to an open conformation within the highly stable SNARE complex. Control of this conformational transition is important for brain function, but the underlying mechanism is unknown.(More)
In the present study, antidepressant-like effects of piperine (PIP) and its derivative, antiepilepsirine (AES), were investigated in two depressive models: forced swimming test (FST) and tail suspension test (TST). To further explore the mechanisms underlying their antidepressant-like activities, the brain monoamine levels and monoamine oxidase A and B(More)
Unc13/Munc13s play a crucial function in neurotransmitter release through their MUN domain, which mediates the transition from the Syntaxin-1/Munc18-1 complex to the SNARE complex. The MUN domain was suggested to be related to tethering factors, but no MUN-domain structure is available to experimentally validate this notion and address key unresolved(More)
Serum microRNAs (miRNAs) have become a highlighted research hotspot, especially for their great potential as a novel promising non-invasive biomarker in cancer diagnosis. The most frequently used approach for serum miRNAs detection is quantitative real time polymerase chain reaction (qPCR). In order to obtain reliable qPCR data of miRNAs expression, the use(More)
Synaptic communication is highly regulated process of contact between cells allowing information to be stored and modified. Synaptic formation and maturation is the result of interactions between intrinsic genetic/molecular factors and the external environment to establish the communication in the brain. One disorder associated with faulty synapse(More)