Wei-Li Liu

Xiao-Gang Jiang2
Cynthia Gaines2
2Xiao-Gang Jiang
2Cynthia Gaines
2Michael Ackerman
Learn More
BACKGROUND The transcriptional activation function of the p53 tumour suppressor protein is induced by DNA damage and results in growth arrest and/or apoptotic responses. A key component of this response is the dramatic rise in p53 protein concentration resulting from an increase in the protein's stability. Very recently, it has been suggested that(More)
INTRODUCTION In 2004, the National Library of Medicine (NLM) recognized the need to expand its outreach activities to minority students. To meet this objective, NLM sponsored a program presenting information on varied health sciences topics to minority students interested in health sciences careers. An existing initiative, NLM's Adopt-A-School program,(More)
Traumatic brain injury (TBI) results in neuronal apoptosis, autophagic cell death and necroptosis. Necroptosis is a newly discovered caspases-independent programmed necrosis pathway which can be triggered by activation of death receptor. Previous works identified that necrostatin-1 (NEC-1), a specific necroptosis inhibitor, could reduce tissue damage and(More)
The vertebrate retina is a distinctly laminar structure. Functionally, the inner plexiform layer, in which bipolar cells synapse onto amacrine and ganglion cells, is subdivided into two sublaminae. Cells that depolarize at light offset ramify in sublamina a; those that depolarize at light onset ramify in sublamina b. The separation of ON and OFF pathways(More)
BACKGROUND The National Library of Medicine's National Center for Biotechnology Information offers mini-courses which entail applying concepts in biochemistry and genetics to search genomics databases and other information sources. They are highly interactive and involve use of 3D molecular visualization software that can be computationally taxing. (More)
INTRODUCTION The quality and performance of several videoconferencing applications (apps) tested on iOS (Apple, Cupertino, CA) and Android (Google, Mountain View, CA) mobile platforms using Wi-Fi (802.11), third-generation (3G), and fourth-generation (4G) cellular networks are described. MATERIALS AND METHODS The tests were done to determine how well apps(More)
OBJECTIVE The study tested the efficacy of providing distance learning with real-time videoconferencing to broaden high school student knowledge of health careers. METHODS A pilot program was tried out and extended over ten years to include other schools in four different time zones and the National Library of Medicine. Survey results, site visits, and(More)
Schizophrenia is one of the common mental diseases. Because the mechanism of the schizophrenia is significantly complicated, the cause is still unknown. N-methyl-D-aspartate receptor antagonist can simulate the positive and negative symptoms, as well as the cognitive disorder of schizophrenia. Thus it has been widely used to establish the animal models of(More)
Ketamine is a phencyclidine derivative acting primarily as a noncompetitive antagonist of N-methyl-D-aspartate (NMDA) excitatory glutamate receptors. As a common intravenous anaesthetic in clinic, it is also increasingly abused because of its hallucination and addiction effects. Based on the pharmacological and toxicologic characteristics of ketamine and(More)
Grid technologies allow for distributed computing and collaboration. Scientists and others utilizing grid collaboration tools often need to share resources using applications besides seeing and hearing each other with audio and video. The ability to share applications in real time is crucial for distant learning and remote collaboration. Web browser sharing(More)
  • 1