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Mobile social networks extend social networks in the cyberspace into the real world by allowing mobile users to discover and interact with existing and potential friends who happen to be in their physical vicinity. Despite their promise to enable many exciting applications, serious security and privacy concerns have hindered wide adoption of these networks.(More)
The optic tectum is central for transforming incoming visual input into orienting behavior. Yet it is not well understood how this behavior is organized early in development and how it relates to the response properties of the developing visual system. We designed a novel behavioral assay to study the development of visually guided behavior in Xenopus(More)
Much of the information processing in the brain occurs at the level of local circuits; however, the mechanisms underlying their initial development are poorly understood. We sought to examine the early development and plasticity of local excitatory circuits in the optic tectum of Xenopus laevis tadpoles. We found that retinal input recruits persistent,(More)
The explosive growth of cellular traffic and its highly dynamic nature often make it increasingly expensive for a cellular service provider to provision enough cellular resources to support the peak traffic demands. In this paper, we propose iDEAL, a novel auction-based incentive framework that allows a cellular service provider to leverage resources from(More)
Single-nucleotide polymorphisms (SNPs) in pre-miRNAs may alter microRNA expression levels or processing and then contribute to the susceptibility of cancer development. We hypothesized that SNPs in pre-miRNAs may be associated with the risk of colorectal cancer (CRC). We genotyped four common polymorphisms (i.e., rs11614913, rs3746444, rs2910164, and(More)
OBJECTIVE(S) Accumulating evidence has demonstrated that miRNAs contribute to various genetic and epigenetic modifications in the pathogenesis of gastric cancer (GC). Recent studies focused on the four single nucleotide polymorphisms (SNPs) of pre-miRNAs including rs11614913, rs3746444, rs2910164, and rs2292832. It was suggested that these four SNPs were(More)
Crocodilians are diving reptiles that can hold their breath under water for long periods of time and are crepuscular animals with excellent sensory abilities. They comprise a sister lineage of birds and have no sex chromosome. Here we report the genome sequence of the endangered Chinese alligator (Alligator sinensis) and describe its unique features. The(More)
We synthesised the evidence of microRNAs as prognostic biomarkers in lung cancer. Studies were identified by searching PubMed, Embase and Web of Science until March 2012. Descriptive characteristics for studies were described and an additional meta-analysis for two specific microRNAs (miR-21 and miR-155) which were studied extensively was performed. Pooled(More)
OBJECTIVES Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airway obstruction and persistent chronic airway inflammation and is influenced by genetic and environmental factors. This study aimed to explore the genetic aspect of its initial occurrence. DESIGN AND METHODS We conducted a case-control study of 432 COPD patients(More)
As a result of the cochlea's nonlinear mechanics, stimulation by two tones results in the generation of distortion products (DPs) at frequencies flanking the primary tones. DPs are measurable in the ear canal as oto-acoustic emissions, and are used to noninvasively explore cochlear mechanics and diagnose hearing loss. Theories of DP emissions generally(More)