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  • Wei Chen, Dwight Stambolian, +63 authors Anand Swaroop
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2010 (First Publication: 12 April 2010)
  • We executed a genome-wide association scan for age-related macular degeneration (AMD) in 2,157 cases and 1,150 controls. Our results validate AMD susceptibility loci near CFH (P < 10−75), ARMS2 (P <Expand
  • Mark G Manfredi, Jeffrey A. Ecsedy, +17 authors Christopher F. Claiborne
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2007 (First Publication: 6 March 2007)
  • Increased Aurora A expression occurs in a variety of human cancers and induces chromosomal abnormalities during mitosis associated with tumor initiation and progression. MLN8054 is a selectiveExpand
  • Xiu-rong Ren, Eric Reiter, Seungkirl Ahn, Jihee Kim, Wei Chen, Robert J Lefkowitz
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2005 (First Publication: 1 February 2005)
  • Signaling through beta-arrestins is a recently appreciated mechanism used by seven-transmembrane receptors. Because G protein-coupled receptor kinase (GRK) phosphorylation of such receptors isExpand