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Security informatics is an emerging field of study focusing on the development and evaluation of advanced information technologies and systems for national and homeland security-related applications. Spatio-temporal hotspot analysis is an important component of security informatics since location and time are two critical aspects of most security-related(More)
Spatio-temporal data analysis plays a central role in many security-related applications including those relevant to transportation infrastructure and border security. In this paper, we investigate prospective spatio-temporal analysis methods that aim to identify "unusual" clusters of events, or hotspots, in both spatial and temporal dimensions. We propose(More)
Soybean fatty acids (FAs) are major sources of vegetable oil in the world. The FA composition of soybean is associated with the quality and nutritional value of its oil and food products. The polyunsaturated FAs, particularly linolenic acid (LN), are prone to oxidation by lipoxygenase isozymes and negatively affect the flavor and shelf-life of soybean(More)
With rapid advances in e-business and mobile technology, the personalized recommendation of mobile tourism becomes a critical issue for both researchers and practitioners. The big data, problems of new users and similar recommendations remain barriers for mobile tourism. Through a large dataset gathered by questionnaires, this paper develops a novel(More)
Two multisensor multiobservation detection schemes are analyzed and compared, and their hardware complexity (= number of sensors) is discussed. The studied schemes are: a Bayesian optimal parallel-sensor centralized architecture and a suboptimal binary distributed-detection system. Both systems are to have the same performance, as measured in terms of a(More)
PURPOSE A four-generation Chinese family with 13 members affected with autosomal dominant congenital posterior polar cataract was studied. The purpose of this study was to identify the disease-causing gene in the family and to validate that mutations in CRYAB, the alphaB-crystallin gene, cause the congenital cataract. METHODS Linkage analysis was(More)
Lead is a pervasive and persistent environmental pollutant that exerts deleterious effects on all living organisms and continues to threaten public health on a global scale. Heme oxygenase-1 (HO-1) is a stress-inducible enzyme that mediates antioxidative and cytoprotective effects to maintain cellular redox homeostasis and protect cells from oxidative(More)
Motivated by the importance of infectious disease informatics (IDI) and the challenges to IDI system development and data sharing, we design and implement BioPortal, a Web-based IDI system that integrates cross-jurisdictional data to support information sharing, analysis, and visualization in public health. In this paper, we discuss general challenges in(More)